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When using Guanfacine ER (Intuniv), it is crucial to be aware of several important safety considerations. This information outlines potential risks and necessary precautions to ensure safe and effective use. Please consult your healthcare provider if you have any questions or concerns.

• Low Blood Pressure or Heart Rate: Guanfacine ER may lead to a decrease in blood pressure or heart rate, which can result in dizziness or faintness. These effects are more likely when starting the medication or adjusting the dose. Regular monitoring of blood pressure and heart rate by your healthcare provider is essential, especially if you are on medications that also lower blood pressure or heart rate. If dizziness, fatigue, or breathlessness persist, contact your healthcare provider. Conditions such as low blood pressure, heart or kidney problems, a history of fainting, dehydration, or concurrent use of medications affecting blood pressure or heart rate increase the risk of these side effects.

• Extreme Sleepiness: This medication may cause significant drowsiness initially, affecting concentration and reaction times. Avoid activities requiring full alertness, such as driving or operating heavy machinery, until you are accustomed to the medication's effects. If sleepiness continues beyond a few days, seek advice from your healthcare provider. The risk of drowsiness increases if you are taking other sedative medications or consuming alcohol.

• Rebound High Blood Pressure: Abruptly stopping Guanfacine ER can lead to a rebound increase in blood pressure, along with symptoms such as headaches, rapid heart rate, nausea, chest tightness, or heightened anxiety. It is important not to miss doses and to discuss any plans to discontinue the medication with your healthcare provider, who can guide a gradual and safe withdrawal process.

• Heart Problems: Guanfacine ER may increase the risk of irregular heart rhythms. If you are taking other medications that influence heart rhythm, consult your healthcare provider, as medication adjustments may be necessary. Individuals with a history of heart problems should exercise caution.

No specific contraindications have been identified for Guanfacine ER (Intuniv). Always follow your healthcare provider's instructions and report any unusual or persistent side effects.

When taking this medication, some individuals may experience common side effects, including drowsiness, tiredness, dizziness, dry mouth, constipation, nausea, headache, and stomach pain. These effects are generally mild and tend to resolve on their own. To alleviate dry mouth, consider using sugarless candy, ice chips, or gum, and ensure you stay hydrated. Additionally, to minimize dizziness and lightheadedness, rise slowly from sitting or lying positions.

However, it is important to be aware of more serious side effects, though they are rare. Seek immediate medical attention if you experience symptoms such as a dangerously low blood pressure, indicated by extreme dizziness, fatigue, or shortness of breath, or any heart-related problems like lightheadedness, fainting, or an unusually fast heartbeat.

Furthermore, although a severe allergic reaction is uncommon, be vigilant for signs such as rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing, and seek medical help right away if they occur. Always monitor your body's response to the medication and consult with your healthcare provider should you notice any persistent or severe side effects.