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When using this medication, it is important to be aware of potential drug interactions and precautions to ensure your safety. Please consider the following points:

• MAO Inhibitors: Avoid taking this medication with MAO inhibitors (such as isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) as it may lead to a serious, potentially fatal interaction. Most MAO inhibitors should not be used within two weeks prior to starting this treatment. Consult your healthcare provider for guidance on when to commence or discontinue these medications.

• Serotonin Syndrome Risk: Be cautious if you are using other drugs that increase serotonin levels, as this can elevate the risk of serotonin syndrome or toxicity. This includes certain street drugs like MDMA/"ecstasy," herbal supplements such as St. John's wort, and specific antidepressants including SSRIs (e.g., fluoxetine, paroxetine) and SNRIs (e.g., duloxetine, venlafaxine). The risk is particularly heightened when initiating or increasing doses of these medications.

• Ergotamine and Triptan Drugs: If you are taking ergotamine medications (e.g., dihydroergotamine) or triptan drugs (e.g., zolmitriptan, rizatriptan), it is crucial to separate their usage from this medication to minimize the possibility of severe side effects. Your doctor can provide specific advice on the appropriate interval between these doses.

Remember, always consult with your healthcare provider regarding any potential interactions or concerns when using this medication.

Using MAO inhibitors with this medication can lead to a serious, potentially life-threatening reaction. You should not take MAO inhibitors, such as isocarboxazid, linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine, while using this medication. Additionally, most MAO inhibitors must be avoided for at least two weeks before starting this treatment. Consult your doctor for guidance on when to begin or discontinue this medication.

An increased risk of serotonin syndrome or toxicity exists if you take other medications that elevate serotonin levels. These include certain street drugs like MDMA/ecstasy, herbal supplements such as St. John's wort, and specific antidepressants, including SSRIs (e.g., Fluoxetine, paroxetine) and SNRIs (e.g., Duloxetine, Venlafaxine). The risk is higher when initiating or increasing the dosage of these drugs.

If you are also using ergotamine (e.g., Dihydroergotamine) or "triptan" medications (e.g., Zolmitriptan, Rizatriptan), it is important to separate the doses of these drugs from your Sumatriptan dose to minimize the risk of significant side effects. Consult with your doctor about how much time should pass between doses of these medications.