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When considering the use of Kyzatrex (testosterone undecanoate), it is crucial to be aware of potential risks and necessary precautions. Below is an outline of important safety information to guide both patients and healthcare providers.

• High Blood Pressure and Cardiovascular Risks: This medication may increase blood pressure, heightening the risk of severe cardiovascular events like heart attacks or strokes, especially in individuals with existing heart conditions. Regular blood pressure monitoring is advised, and adjustments to your treatment may be necessary if high blood pressure develops.

• Increased Red Blood Cell Count: Kyzatrex can elevate red blood cell counts, potentially leading to blood clots, strokes, or heart attacks. Routine blood tests every three months are recommended to monitor red blood cell levels.

• Blood Clots: There is a risk of developing life-threatening blood clots in the legs or lungs. Seek immediate medical attention if you experience leg pain, swelling, chest pain, or breathing difficulties.

• Potential for Misuse and Dependency: As a controlled substance, Kyzatrex carries a risk of misuse, dependency, and addiction. Misusing this medication can lead to serious heart and mental health issues. Always adhere to prescribed dosages.

• Prostate Health: Kyzatrex may exacerbate symptoms of an enlarged prostate and could increase the risk of prostate cancer. Report any urinary changes to your healthcare provider.

• Liver Concerns: Although Kyzatrex is not known to cause liver issues, be vigilant for symptoms like stomach pain or jaundice, and inform your provider immediately.

• Fertility Considerations: This medication may reduce sperm production, affecting fertility, particularly at higher doses. Discuss with your doctor if you are planning to conceive.

• Edema (Swelling): Kyzatrex can cause fluid retention, leading to swelling in the arms or legs, especially in those with heart, liver, or kidney issues. Notify your provider if swelling occurs.

• Sleep Apnea: The medication may worsen sleep apnea, particularly in those with obesity or lung conditions. Increased daytime sleepiness or observed breathing interruptions during sleep should be reported.

• Hypercalcemia: Elevated calcium levels can occur, especially in patients with cancer, leading to symptoms like muscle weakness and kidney problems. Regular monitoring of calcium levels is advised.

• Contraindications: This medication should not be used if you have breast or prostate cancer, are currently pregnant, or have low testosterone levels not due to specific medical conditions.

In case of an overdose, seek emergency medical attention immediately. Always discuss any concerns or symptoms with your healthcare provider to ensure safe use of Kyzatrex.

When using this medication, some common side effects may include nausea, vomiting, headaches, changes in skin color, oily skin, hair loss, and acne. These are generally mild and should ease over time, but if they persist or worsen, consult your healthcare provider. Additionally, you might experience variations in sexual interest or high blood pressure.

More serious side effects, though less common, require immediate attention. These include mental or mood changes such as anxiety or depression, sleep disturbances including sleep apnea, signs of liver damage like persistent nausea, vomiting, or yellowing of the skin, and swelling of the hands, ankles, or feet. Other significant symptoms include unusual tiredness, a fast or irregular heartbeat, trouble urinating, increased urination at night, breast swelling or tenderness, and frequent or prolonged erections.

In rare cases, very serious side effects can occur, necessitating urgent medical care. These include symptoms indicative of a heart attack, such as chest pain, rapid breathing, or cold sweats; stroke symptoms like sudden dizziness, fainting, or trouble speaking; and blood clots, which may cause pain or swelling in the legs. Painful erections lasting four or more hours and severe allergic reactions signified by rash, swelling, or difficulty breathing also demand immediate medical intervention. Always remain vigilant and seek medical advice if you notice any unusual symptoms.