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This medication, Aveed (testosterone undecanoate), carries certain risks and requires careful monitoring. Below are important safety considerations and warnings to be aware of:

• Pulmonary Oil Microembolism (POME) and Severe Allergic Reactions: Rarely, this medication can cause a serious lung condition known as POME, where small oil droplets travel to the lungs. Symptoms can include coughing, difficulty breathing, sweating, throat constriction, chest pain, dizziness, or fainting. These reactions may occur during or immediately after injection and can last from a few minutes to several hours, potentially requiring emergency medical attention. Patients should remain under medical observation for 30 minutes post-injection.

• Prostate Issues: The use of Aveed can exacerbate symptoms in individuals with an enlarged prostate (BPH). Notify your healthcare provider if you experience changes in urination patterns, such as frequent urination at night, urgency, difficulty, or slow urination.

• Risk of Blood Clots: Testosterone therapy might increase the risk of blood clots, leading to heart attacks or strokes. Regular blood tests will be conducted to monitor your blood cell counts. Seek immediate medical help if you experience chest pain, cold sweats, left arm pain, breathing difficulties, or sudden weakness on one side of the body.

• Potential for Misuse and Dependency: Aveed is a controlled substance due to the risk of misuse and dependency, particularly when taken in higher doses than prescribed or alongside other testosterones.

• Liver Concerns: While not specifically associated with Aveed, long-term use of certain testosterone forms can lead to severe liver damage. Report any symptoms such as stomach pain, light-colored stools, dark urine, or yellowing of the skin or eyes to your healthcare provider.

• Edema (Swelling): This medication may cause fluid retention, leading to swelling in the legs or arms and sudden weight gain. It is particularly concerning for individuals with heart, liver, or kidney issues or those taking corticosteroids.

• Sleep Apnea: Aveed can contribute to sleep apnea, especially in individuals who are obese or have lung issues. Increased daytime sleepiness or observed breathing interruptions during sleep should be discussed with your healthcare provider.

• Hypercalcemia: This medication can elevate calcium levels in the blood, particularly in cancer patients, which could indicate bone metastasis. Regular monitoring of calcium levels is advised.

Contraindications:

• Do not use Aveed if you have breast cancer, prostate cancer, or are currently pregnant. Always consult a healthcare professional before starting this medication.

When using this medication, some common side effects may include nausea, vomiting, headaches, and changes in skin color. Many people also report oily skin, hair loss, acne, and changes in sexual interest. You might experience pain or redness at the injection site as well. While these effects are generally mild, if they persist or worsen, discussing them with a healthcare provider is advisable. This medication may also increase blood pressure, so regular monitoring is recommended.

On the more serious side, some individuals may encounter side effects that require immediate medical attention. These include swelling or tenderness of the breasts, significant mood changes such as depression or hostility, and unusual snoring or sleep difficulties. Swelling in the hands, ankles, or feet, as well as symptoms indicating liver issues like persistent nausea or yellowing of the skin and eyes, should be addressed promptly. Additionally, difficulty urinating, rapid heartbeat, and prolonged erections are concerning and should be reported to a healthcare provider quickly.

Rarely, severe allergic reactions might occur, featuring symptoms like rash, itching, or swelling, especially of the face and throat. Serious conditions such as a heart attack or stroke manifest through symptoms like chest pain, severe headaches, or sudden vision changes and require urgent medical intervention. Other severe side effects include blood clots, trouble breathing, and signs of liver damage. If any of these symptoms appear, seeking immediate medical help is crucial to prevent lasting harm.

When using Aveed (testosterone undecanoate), it's important to be aware of potential interactions with certain medications. This drug can particularly interact with blood thinners like Warfarin, acenocoumarol, anisindione, dicumarol, phenindione, and phenprocoumon. These interactions may necessitate adjustments to your medication regimen. Additionally, cholesterol-lowering medications such as Simvastatin, Atorvastatin, Fluvastatin, and Lovastatin, among others, can also interact with Aveed. In some cases, your doctor may need to modify the dosages or usage frequency of these drugs if they are prescribed alongside Aveed.

Moreover, Aveed may impact the results of certain lab tests, such as thyroid function tests, potentially leading to inaccurate results. It is crucial for lab technicians and all healthcare providers involved in your care to be informed about your use of Aveed. Always discuss with your doctor and pharmacist any other medications, supplements, or herbal products you are taking to ensure safe and effective treatment.