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This medication requires careful consideration of several important safety warnings and contraindications. Please review the information below and consult your healthcare provider with any questions or concerns.

• Dizziness and Vision Impairment: Hyoscyamine can lead to drowsiness, dizziness, and blurred vision. Until you are aware of how the medication affects you, refrain from driving or engaging in activities that demand high levels of attention.

• Mental and Behavioral Changes: This medication may alter your mood, thoughts, or cognitive abilities, with possible symptoms including confusion, memory lapses, disorientation, agitation, hallucinations, or euphoria. In severe cases, it might result in a coma. These effects typically resolve within 12 to 48 hours after discontinuation. Notify your healthcare provider immediately if you experience any changes in mood, thoughts, or behaviors, especially if you are 65 or older or have mental health conditions.

• Increased Heart Rate: Hyoscyamine can accelerate your heart rate, exacerbating conditions like heart failure, prior heart attacks, or hypertension. Inform your healthcare provider if you detect a change in your heart rate or experience a pounding or racing heart. Individuals with heart problems or high blood pressure are at higher risk.

• Autonomic System Changes: The medication may impact involuntary body functions, such as slowing gut movements, causing constipation, reducing saliva or sweat production, leading to dry mouth and thirst, or increasing the risk of heat stroke. It can also affect heart rate and vision. Inform your provider of any bodily function changes, and avoid taking hyoscyamine during a fever without medical advice, especially if you are 65 or older.

• Urinary Difficulties: Use with caution if you have prostate issues, as hyoscyamine can worsen urinary problems.

• Gastrointestinal Caution: If you have had a colostomy or similar procedures, inform your provider before using hyoscyamine for diarrhea, as it could indicate a bowel obstruction, which may be worsened by this medication.

Contraindications: Hyoscyamine should not be used if you have the following conditions, as it may pose serious health risks:

• Glaucoma
• Urinary tract obstruction
• Gastrointestinal blockages
• Chronic constipation
• Unstable heart conditions or bleeding disorders
• Severe ulcerative colitis with toxic megacolon
• Myasthenia gravis

Always consult your healthcare provider if any of these conditions apply to you before taking hyoscyamine.

When taking Levsin, it's important to be aware of potential interactions with other substances that could affect its effectiveness or increase the risk of side effects. Here are some key considerations:

Interactions with Other Medications:

• Anticholinergic Drugs: Combining Levsin with other anticholinergic medications, such as certain antihistamines, tricyclic antidepressants, or medications for Parkinson's disease, can intensify side effects like dry mouth, blurred vision, constipation, and difficulty urinating.

• Antacids: Antacids may interfere with the absorption of Levsin. To minimize this interaction, it's recommended to take Levsin before meals and antacids after meals.

• Alcohol: Consuming alcohol while taking Levsin can enhance drowsiness and dizziness. It's advisable to limit or avoid alcohol during treatment.

Food Interactions:

• Levsin should be taken 30 to 60 minutes before meals to ensure optimal absorption and effectiveness.

Disease Interactions:

• Levsin may exacerbate certain conditions, including glaucoma, obstructive uropathy, gastrointestinal obstructions, and myasthenia gravis. Patients with these conditions should use Levsin cautiously and under medical supervision.

Always inform your healthcare provider about all medications, supplements, and underlying health conditions before starting Levsin to ensure safe and effective use.