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This medication requires careful consideration of several important safety warnings and contraindications. Please review the information below and consult your healthcare provider with any questions or concerns.

• Dizziness and Vision Impairment: Hyoscyamine can lead to drowsiness, dizziness, and blurred vision. Until you are aware of how the medication affects you, refrain from driving or engaging in activities that demand high levels of attention.

• Mental and Behavioral Changes: This medication may alter your mood, thoughts, or cognitive abilities, with possible symptoms including confusion, memory lapses, disorientation, agitation, hallucinations, or euphoria. In severe cases, it might result in a coma. These effects typically resolve within 12 to 48 hours after discontinuation. Notify your healthcare provider immediately if you experience any changes in mood, thoughts, or behaviors, especially if you are 65 or older or have mental health conditions.

• Increased Heart Rate: Hyoscyamine can accelerate your heart rate, exacerbating conditions like heart failure, prior heart attacks, or hypertension. Inform your healthcare provider if you detect a change in your heart rate or experience a pounding or racing heart. Individuals with heart problems or high blood pressure are at higher risk.

• Autonomic System Changes: The medication may impact involuntary body functions, such as slowing gut movements, causing constipation, reducing saliva or sweat production, leading to dry mouth and thirst, or increasing the risk of heat stroke. It can also affect heart rate and vision. Inform your provider of any bodily function changes, and avoid taking hyoscyamine during a fever without medical advice, especially if you are 65 or older.

• Urinary Difficulties: Use with caution if you have prostate issues, as hyoscyamine can worsen urinary problems.

• Gastrointestinal Caution: If you have had a colostomy or similar procedures, inform your provider before using hyoscyamine for diarrhea, as it could indicate a bowel obstruction, which may be worsened by this medication.

Contraindications: Hyoscyamine should not be used if you have the following conditions, as it may pose serious health risks:

• Glaucoma
• Urinary tract obstruction
• Gastrointestinal blockages
• Chronic constipation
• Unstable heart conditions or bleeding disorders
• Severe ulcerative colitis with toxic megacolon
• Myasthenia gravis

Always consult your healthcare provider if any of these conditions apply to you before taking hyoscyamine.

When taking this medication, some people may experience common side effects that are usually mild but can be bothersome if they persist. These include dry mouth, trouble urinating, constipation, blurry vision, dry eyes, sleepiness, dizziness, headache, flushing, and heat intolerance. If these effects do not go away or become troublesome, it's advisable to consult a healthcare provider.

There are other side effects that have been reported occasionally, such as a fast heart rate, diarrhea, confusion, and short-term memory loss. While these are less common, it's important to contact a healthcare professional if they occur, particularly if they are severe.

In rare cases, some individuals might encounter serious side effects that demand immediate medical attention. These include severe changes in mood, thoughts, or behavior, such as psychosis, agitation, hallucinations, confusion, or euphoria. Additionally, an irregular heartbeat, which may manifest as fainting, dizziness or lightheadedness, chest discomfort, shortness of breath, or fatigue, is a critical concern that requires urgent care.