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Norethindrone, commonly known as the "mini-pill," is a progestin-only oral contraceptive designed to prevent pregnancy. It is ideal for women who cannot take estrogen. This medication works by thickening the cervical mucus to hinder sperm movement, altering the uterine lining to prevent implantation of a fertilized egg, and in some cases, preventing ovulation. While norethindrone is more effective than barrier methods like condoms or diaphragms, it is slightly less effective than combination hormonal contraceptives that include estrogen. It is important to take norethindrone at the same time every day to maintain its effectiveness. This medication does not provide protection against sexually transmitted infections such as HIV, gonorrhea, or chlamydia. Common side effects may include irregular bleeding, headaches, and nausea. Always consult with a healthcare professional before starting any new medication.