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Experiencing nausea or a headache is common with this medication, but if these symptoms persist or worsen, it's important to inform your healthcare provider. Usually, individuals taking this medication do not encounter serious side effects. However, be alert for any serious reactions such as dizziness, fainting, an irregular or rapid heartbeat, changes in mood or mental state like anxiety or irritability, shaking, trouble sleeping, or painful urination. These require immediate medical attention.

Although rare, a severe allergic reaction can occur. Seek emergency help if you experience symptoms like a rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. Remember, this list doesn't cover all possible side effects. If you experience any other unexpected symptoms, contact your healthcare provider for guidance.

Avoid using MAO inhibitors with this medication, as doing so can lead to a severe and potentially life-threatening interaction. MAO inhibitors include drugs like isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine. You should not take most MAO inhibitors during treatment with this medication and for two weeks prior to beginning treatment. Consult your doctor about when it is safe to start or stop this medication.

Both prescription and over-the-counter products may contain pseudoephedrine and guaifenesin. Carefully read the labels of all your medications to ensure you are not inadvertently taking more than one product with these ingredients.

This medication can affect certain laboratory tests, such as those measuring urine levels of specific acids, potentially leading to incorrect results. Inform lab personnel and all your healthcare providers that you are using this medication.