Selegiline

Drug Details

Selegiline is a medication prescribed to manage symptoms of Parkinson's disease, particularly for individuals experiencing "off" episodes as their carbidopa/levodopa treatment diminishes. While it does not cure Parkinson's, selegiline can help alleviate tremors, muscle stiffness, and improve movement, thereby enhancing daily activities such as walking, dressing, and exercising. It is typically used in conjunction with other medications like levodopa and carbidopa. Selegiline functions as a monoamine oxidase type B (MAO-B) inhibitor, which works by slowing the breakdown of neurotransmitters such as dopamine in the brain. By preserving dopamine levels, it helps reduce movement-related issues associated with Parkinson’s. Available in tablet and orally disintegrating tablet forms, selegiline can be taken up to twice a day. Patients should be aware of potential side effects, including changes in blood pressure, nausea, and dizziness, and consult healthcare professionals for personalized advice and to manage interactions with other medications.