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This safety information outlines important warnings and precautions associated with the use of Namzaric (memantine / donepezil ER). It is essential to review these carefully and discuss any concerns with your healthcare provider.

• Slowed Heartbeat: Namzaric may reduce your heart rate, potentially causing fainting. Inform your healthcare provider if you experience falls or feelings of lightheadedness.

• Stomach Ulcers and Bleeding: This medication can increase stomach acid production, heightening the risk of ulcers and bleeding. Avoid using NSAIDs and certain over-the-counter cold and pain medications concurrently, as they can further elevate this risk. Contact your healthcare provider if you notice worsening stomach upset, heartburn, indigestion, or blood in your stool, especially if you have a history of stomach ulcers or bleeds.

• Nausea and Vomiting: Common side effects include nausea, vomiting, and diarrhea, usually subsiding within 1 to 3 weeks. Report to your healthcare team if these symptoms become troublesome or interfere with your daily medication intake.

• Urination Problems: Namzaric may obstruct bladder flow, leading to urinary difficulties or pain. Notify your healthcare provider if you experience any changes in urination.

• Seizures: While seizures are sometimes associated with Alzheimer's disease, Namzaric may also trigger them. Consult your healthcare provider if you encounter seizures while using this medication.

• Worsening Lung Conditions: Caution is advised for those with lung conditions such as asthma or COPD, as donepezil can narrow airways by increasing acetylcholine levels, potentially aggravating these conditions. Discuss with your healthcare provider if you have a history of breathing issues to assess medication suitability.

Contraindications include any known allergy to piperidine medications, such as trihexyphenidyl. If this applies to you, seek advice from your healthcare provider before starting Namzaric.

When taking this medication, you may experience some common side effects that are usually mild and temporary. These include headache, diarrhea, nausea, vomiting, dizziness, loss of appetite, bruising, and weight gain. Some individuals might also notice back pain, drowsiness, or dizziness. If these symptoms persist or become bothersome, it is advisable to consult with your healthcare provider for guidance.

There are other side effects that some users have reported, such as constipation, trouble sleeping, sleepiness, and changes in blood pressure. Emotional effects like depression, nervousness, or aggressive behavior, as well as skin reactions like eczema, may also occur. Although these are less common, if they present and are severe, seeking medical advice is recommended.

In rare cases, serious side effects can occur, demanding immediate medical attention. These include irregular heartbeat, fainting, seizures, and severe dizziness. Be alert for signs of stomach or intestinal bleeding, such as black or bloody stools and vomit resembling coffee grounds, as well as severe stomach pain. If you experience difficulty breathing, wheezing, or a very serious allergic reaction, including rash, itching, or swelling especially of the face, tongue, or throat, seek emergency medical help right away.

Always communicate with your healthcare provider about any side effects you encounter, especially if they are not listed here. Remember, while these effects can occur, they do not affect everyone, and many people take this medication without serious complications.