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When taking this medication, you might experience some common side effects such as drowsiness, dizziness, dry mouth, nose, or throat, headaches, upset stomach, constipation, or trouble sleeping. These are generally mild, but if they persist or worsen, it's important to consult your healthcare provider.

In rare instances, more serious side effects can occur. Be vigilant for symptoms like mental or mood changes (including confusion or hallucinations), ringing in the ears, difficulty urinating, or vision changes such as blurred or double vision. These warrant immediate medical attention.

Very serious side effects, though uncommon, require urgent medical intervention. These include a fast or irregular heartbeat and seizures. Additionally, although a serious allergic reaction to this medication is rare, seek immediate help if you experience symptoms like a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing.

This list may not cover all possible side effects. If you notice other unusual symptoms, contact your healthcare provider for advice.

Some items that could interact with this medication include skin-applied antihistamines like diphenhydramine cream, ointment, or spray. Additionally, taking this medication with MAO inhibitors can lead to a severe, potentially life-threatening reaction. It's important to avoid using MAO inhibitors, such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine, while on this medication. Most MAO inhibitors should also be avoided for two weeks before starting this treatment. Consult your doctor on when to begin or discontinue this medication safely.

Inform your doctor or pharmacist if you are taking other substances that cause drowsiness, such as opioid painkillers or cough suppressants like codeine and hydrocodone, alcohol, cannabis, sleep or anxiety medications like Alprazolam, Lorazepam, Zolpidem, muscle relaxants like Carisoprodol or Cyclobenzaprine, or other antihistamines such as Cetirizine or diphenhydramine.

Check the labels of all medications you use (including allergy or cold remedies) as they may contain ingredients that induce drowsiness. Ask your pharmacist for guidance on the safe use of these products. This medication might interfere with certain lab tests (like brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests), potentially leading to inaccurate results. Ensure all your healthcare providers and lab personnel are aware of your medication use.