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When considering the use of this medication, it is vital to be aware of the associated risks and necessary precautions. Below are key safety warnings and instructions to help guide safe use and to recognize when this medication may not be suitable for you.

• Cigarette Smoking and Heart Risks: Smoking while using hormonal birth control, like Yasmin, significantly increases the risk of serious cardiovascular events such as stroke, heart attack, and blood clots. This risk is especially pronounced in women over the age of 35 who smoke. It is strongly advised not to smoke or use tobacco products while taking this medication.

• Blood Clots and Stroke: Yasmin can elevate the risk of developing blood clots, which may occur in various parts of the body, including the lungs, legs, brain, and heart. Immediate medical attention is required if symptoms of a blood clot appear, such as sudden shortness of breath or severe leg pain. Those at heightened risk include women over 35 who smoke, individuals who are obese, people with high blood pressure, and those who have recently undergone surgery or childbirth.

• Cancer Risks: There is a potential increased risk of breast and cervical cancer with prolonged use of Yasmin. Individuals with a history of breast cancer should discuss the risks with their healthcare provider before starting this medication.

• Liver Concerns: Yasmin might cause liver damage or tumors, although this is rare. If you have existing liver conditions, it's crucial not to use this medication. Watch for symptoms like fatigue, abdominal pain, or jaundice, and consult your provider immediately if these occur.

• Blood Pressure and Sugar Levels: This medication can cause a rise in blood pressure and may affect blood sugar and lipid levels. Regular monitoring by your healthcare provider is recommended, especially if you have conditions such as diabetes or high triglycerides.

• Headaches and Depression: New or worsening headaches, particularly migraines, should be reported to your provider. Likewise, any signs of depression or mood changes should be communicated, as serious symptoms might necessitate discontinuation of the medication.

• Drug Interactions: Some medications can alter the effectiveness of Yasmin, potentially leading to unintended pregnancy or increased side effects. Inform your healthcare provider of all medications you are taking to ensure compatibility.

• Potassium Levels: Yasmin contains drospirenone, which can elevate potassium levels in the body. Monitoring is advised for those with kidney, liver, or adrenal issues, or those taking other medications that affect potassium levels.

Contraindications:

• Do not use Yasmin if you have kidney, liver, or adrenal gland problems, a high risk of blood clots, certain heart conditions, uncontrolled high blood pressure, diabetes, or if you are pregnant.
• It is also contraindicated for individuals with a history of breast cancer, severe migraines, or those currently treated with specific medications like Viekira Pak.

Always consult with your healthcare provider to determine if Yasmin is appropriate for you and to discuss any concerns or questions about its use.

When taking this medication, mild side effects are possible. Many people may experience nausea, vomiting, headaches, bloating, breast tenderness, and swelling of the ankles or feet due to fluid retention. These symptoms, along with weight changes and premenstrual syndrome, are generally not severe, but if they persist or worsen, it's important to consult your healthcare provider.

Some individuals may notice changes in their menstrual cycle, such as spotting, missed, or irregular periods, particularly during the initial months of use. Stomach discomfort and mood changes, including depression, may also occur. Monitoring blood pressure is advised, as this medication can increase it. If high blood pressure is detected, seek medical advice.

Though uncommon, serious side effects necessitate prompt medical attention. These include unusual vaginal bleeding, high potassium levels manifesting as muscle weakness or an irregular heartbeat, and severe allergic reactions like rash or difficulty breathing. Blood clots are a rare but severe risk, potentially leading to heart attacks, strokes, or deep vein thrombosis. Symptoms to watch for include chest pain, sudden dizziness, severe headaches, and shortness of breath. Additionally, liver issues may present as yellowing skin or eyes.

Always seek immediate medical help if experiencing severe side effects, and report any other unexpected symptoms to your healthcare provider.

If you're taking Yasmin, it's important to be aware of potential interactions with other medications or supplements. Always inform your doctor and pharmacist about all the medications and supplements you use, whether they are prescribed, over-the-counter, vitamins, or herbal products.

Yasmin should generally not be combined with certain medications, including Boceprevir, Dasabuvir, Ombitasvir, Paritaprevir, Ritonavir, and Tranexamic Acid, as these can lead to significant interactions.

There are also medications that are usually not recommended to be used with Yasmin, though in some cases, your doctor might prescribe them together with adjustments. These include drugs such as Amifampridine, Amoxicillin, Ampicillin, and many others listed in the detailed section above.

Additionally, some medications may increase the risk of side effects when used with Yasmin, but your doctor may decide the benefit outweighs the risk. Examples include Amitriptyline, Atazanavir, and others.

Furthermore, Yasmin may affect your potassium levels. If you take medications like ACE inhibitors (e.g., enalapril, lisinopril), angiotensin receptor blockers (e.g., losartan, valsartan), or potassium-sparing diuretics (e.g., spironolactone), inform your doctor, as these can also increase your potassium levels.

Certain drugs can reduce the effectiveness of hormonal birth control like Yasmin, possibly leading to pregnancy. Examples include drugs for seizures, some antibiotics, and herbal supplements like St. John's wort. If you experience unusual spotting or bleeding, contact your doctor, as these could indicate reduced effectiveness of your birth control.

Lastly, Yasmin may interfere with some lab tests, potentially causing incorrect results. Always inform healthcare personnel that you are taking this medication.