Orkambi
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$24,542.23
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AlbertsonsPowered byAbout Orkambi
Drug Details
Orkambi is a medication composed of lumacaftor and ivacaftor, designed to treat cystic fibrosis in patients who are 2 years and older. It specifically targets individuals with two copies of the F508del mutation in the CFTR gene. By improving respiratory function, reducing lung infection risks, and aiding in weight gain, Orkambi helps manage the symptoms of cystic fibrosis. It is generally dispensed through select pharmacies.
Price history for Orkambi
112 Tablets, 100-125MG
Average retail price for Orkambi
Average SaveHealth price for Orkambi
Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.
*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.
Orkambi dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 100-125MG | 112 Tablets | $24,542.23 | $219.13 |
| 200-125MG | 112 Tablets | $24,542.23 | $219.13 |
Orkambi FAQs
ORKAMBI is used for the treatment of cystic fibrosis in patients who are 2 years of age and older and have two copies of the F508del mutation in the CFTR gene. It works by improving the function of the defective protein made by the CFTR gene, thereby helping to manage the symptoms of cystic fibrosis.
The cost of ORKAMBI can vary significantly based on factors such as insurance coverage, pharmacy, and location. Without insurance, the list price can be quite high, often exceeding several hundred thousand dollars annually. Patients are encouraged to check with their insurance provider for specific coverage details and potential out-of-pocket costs. Additionally, Vertex Pharmaceuticals, the manufacturer, offers a patient assistance program that may help reduce costs for eligible individuals.
Yes, ORKAMBI is approved by the FDA. It was first approved in July 2015 for the treatment of cystic fibrosis in patients aged 12 years and older with specific genetic mutations.
Trikafta is considered more effective than Orkambi for many patients with cystic fibrosis because it targets a broader range of CFTR mutations, including the most common F508del mutation. Trikafta combines three medications (elexacaftor, tezacaftor, and ivacaftor) that work together to improve the function of the CFTR protein more effectively than the two-drug combination in Orkambi (lumacaftor and ivacaftor). This results in better lung function, fewer pulmonary exacerbations, and improved quality of life for many patients.
The cost of ORKAMBI without insurance can vary, but it is generally quite expensive. As of the latest information, the price can be around $20,000 to $30,000 for a 28-day supply. Prices may vary based on the pharmacy and location. It is advisable to check with local pharmacies for the most accurate pricing.