Orkambi Coupons & Savings Card – Discount Prices from $23990.13

ORKAMBI is used for the treatment of cystic fibrosis in patients who are 2 years of age and older and have two copies of the F508del mutation in the CFTR gene. It works by improving the function of the defective protein made by the CFTR gene, thereby helping to manage the symptoms of cystic fibrosis.

The cost of ORKAMBI can vary significantly based on factors such as insurance coverage, pharmacy, and location. Without insurance, the list price can be quite high, often exceeding several hundred thousand dollars annually. Patients are encouraged to check with their insurance provider for specific coverage details and potential out-of-pocket costs. Additionally, Vertex Pharmaceuticals, the manufacturer, offers a patient assistance program that may help reduce costs for eligible individuals.

Yes, ORKAMBI is approved by the FDA. It was first approved in July 2015 for the treatment of cystic fibrosis in patients aged 12 years and older with specific genetic mutations.

Trikafta is considered more effective than Orkambi for many patients with cystic fibrosis because it targets a broader range of CFTR mutations, including the most common F508del mutation. Trikafta combines three medications (elexacaftor, tezacaftor, and ivacaftor) that work together to improve the function of the CFTR protein more effectively than the two-drug combination in Orkambi (lumacaftor and ivacaftor). This results in better lung function, fewer pulmonary exacerbations, and improved quality of life for many patients.

The cost of ORKAMBI without insurance can vary, but it is generally quite expensive. As of the latest information, the price can be around $20,000 to $30,000 for a 28-day supply. Prices may vary based on the pharmacy and location. It is advisable to check with local pharmacies for the most accurate pricing.