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This medication comes with important safety warnings that you should review carefully. Consult your healthcare provider if you have any questions or concerns regarding its use.

• High calcium or vitamin D levels: Avoid using calcium carbonate/vitamin D3 if you have elevated levels of calcium or vitamin D in your bloodstream. Exceeding the recommended dose can lead to a harmful buildup of calcium, potentially affecting kidney function. Regular blood tests are necessary to monitor your calcium and vitamin D levels and ensure you are on the correct dose. Contact your healthcare provider if you experience persistent nausea, loss of appetite, weight loss, constipation, muscle pain or stiffness, or changes in urination patterns.

• Risk of high doses and interactions: Be cautious with high doses of calcium carbonate/vitamin D3 and when using other medications containing calcium or vitamin D. Interactions may occur with many medications, including over-the-counter and prescription drugs. Inform your healthcare provider of all medications you are taking, particularly bisphosphonates, quinolone antibiotics, tetracyclines, or iron supplements. These may require timing adjustments to avoid interactions. Always consult with your provider or pharmacist before starting any new medications to ensure they can be safely combined with calcium carbonate/vitamin D3.

There are no specific contraindications listed for this medication, but always follow your healthcare provider's guidance and recommendations.

Common side effects:

• Loss of appetite
• Nausea
• Weakness
• Weight loss
• Muscle aches
• Stiffness
• Constipation
• Changes in urination patterns
• Persistent fatigue
• Swelling in the legs or feet

Less common but important to monitor:

• Allergic reactions (skin rash, itching, hives, swelling of the face, lips, tongue, or throat)
• Increased thirst
• Frequent urination
• Nausea
• Vomiting
• Confusion
• Unusual weakness or fatigue
• Bone pain

Serious side effects:

• Severe constipation
• Significant loss of appetite
• Persistent nausea
• Upset stomach
• Vomiting

When taking Oysco 500 with D, a supplement containing calcium and vitamin D, it's important to be aware of potential interactions with other medications and certain health conditions. Calcium can interfere with the absorption of various drugs, including tetracycline and quinolone antibiotics, bisphosphonates, estramustine, and Levothyroxine. To minimize this effect, it's advisable to take these medications at least two hours before or four to six hours after consuming calcium supplements. Additionally, certain medications, such as bile acid sequestrants (like Cholestyramine or Colestipol), Mineral Oil, and Orlistat, can reduce the absorption of vitamin D. Therefore, it's recommended to separate the intake of these medications from Oysco 500 with D by several hours.

Individuals with specific health conditions should exercise caution when using Oysco 500 with D. Those with kidney disease, kidney stones, heart disease, cancer, high levels of calcium in the blood, circulation problems, or parathyroid gland disorders should consult their healthcare provider before starting this supplement. Monitoring of calcium and vitamin D levels may be necessary to prevent complications.

It's also important to consider dietary factors. Foods high in oxalic acid (such as spinach and rhubarb) or phytic acid (found in bran and whole grains) can decrease calcium absorption. To enhance calcium uptake, consider spacing the consumption of these foods at least two hours apart from taking Oysco 500 with D.

Always inform your healthcare provider about all medications, supplements, and dietary habits to ensure safe and effective use of Oysco 500 with D.