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Podophyllum resin is used primarily for the treatment of external genital warts and perianal warts. It is applied topically to the affected area to help remove the warts. It is important to follow a healthcare provider's instructions when using this medication, as it can be toxic if used improperly.

Yes, podophyllum resin is toxic. It should be used with caution and only under the guidance of a healthcare professional. It is important to avoid ingestion and to apply it only to the affected area as directed, as improper use can lead to serious side effects.

Podophyllum resin can cause several side effects. Commonly, it may lead to local skin reactions such as redness, itching, burning, or irritation at the site of application. In some cases, it can cause blistering or ulceration. Systemic absorption can lead to more severe effects, including nausea, vomiting, diarrhea, abdominal pain, and in rare cases, neurotoxicity or hematological effects. It is important for individuals to use this medication under medical supervision to minimize risks.

Yes, podophyllin can cause a burning sensation when applied. It is a caustic agent used to treat certain skin conditions, and some degree of irritation or discomfort is common. If the burning is severe or persistent, it is advisable to consult a healthcare professional.