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Here are the important safety and warning details you need to be aware of when using Qbrexza (glycopyrronium). Please read these carefully and discuss any concerns with your healthcare provider.

• Urinary Problems: Qbrexza (glycopyrronium), like other anticholinergic medications, may lead to difficulty with urination. If you have a history of bladder issues, this could worsen your condition. Stop using the medication immediately if you experience trouble urinating and inform your healthcare provider at the first sign of symptoms. Be particularly cautious if you have an enlarged prostate or a bladder blockage.

• Risk of Heat Stroke and High Body Temperatures: This medication increases the risk of heat strokes and elevated body temperatures, especially in hot conditions. Normally, sweating helps regulate body temperature, but Qbrexza (glycopyrronium) reduces sweating, which can lead to overheating. If you experience reduced sweating, red and hot skin, fever, dizziness, or trouble breathing, discontinue use and contact your healthcare provider immediately. Take extra care if you are on another anticholinergic drug or exposed to warm environments.

• Blurred Vision: Temporary blurred vision can occur while using Qbrexza (glycopyrronium), typically resolving on its own. During this time, avoid driving, operating heavy machinery, or any activities that require clear vision. If blurred vision occurs, stop taking the medication and consult your healthcare provider promptly. This is especially important if you are taking another anticholinergic medication.

Contraindications: Do not use Qbrexza (glycopyrronium) if you have any of the following conditions, as it may cause serious health complications. Consult your healthcare provider before starting this medication if:

• You have glaucoma.
• You have a stomach or intestinal blockage.
• You have unstable heart health during periods of severe bleeding.
• You suffer from severe ulcerative colitis.
• You have myasthenia gravis.
• You are diagnosed with Sjogren’s syndrome.

Please ensure you adhere to these guidelines to use Qbrexza safely.

When using this medication, some common side effects may arise, though they are often mild and manageable. These include dryness in the mouth, nose, throat, or skin, as well as redness, burning, or stinging at the application site. You might also experience an itchy sensation, headaches, blurred vision, a sore throat, and occasionally, widening of the pupils. If these symptoms persist or worsen, it's advisable to consult with a healthcare provider for further guidance.

Other side effects, while not as common, have been noted and should be monitored. These include difficulty urinating, blurry vision, and constipation. If you notice any of these symptoms, reaching out to your healthcare provider can help manage them effectively.

Serious side effects, though rare, require immediate attention and should not be overlooked. Seek urgent medical care if you experience symptoms such as allergic reactions, which may present as a rash, itching, hives, or swelling of the face, lips, tongue, or throat. Additionally, if there are signs of burning, itching, crusting, or peeling of the treated skin, persistent fever, decreased sweating, or trouble passing urine, prompt medical evaluation is necessary to ensure your safety and well-being.