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This document outlines crucial safety information and warnings regarding the use of the medication Qulipta (atogepant). It is important to carefully read the following points and discuss any concerns with your healthcare provider.

• Allergic Reactions: Be aware that Qulipta (atogepant) may cause allergic reactions, which could be severe or life-threatening. Symptoms may include swelling of the face, shock, or anaphylaxis characterized by throat closure. Such reactions might occur even days after taking the medication. Seek immediate medical assistance if you experience dizziness, a choking sensation, difficulty breathing, nausea, or swelling around the eyes, lips, or tongue.

Please ensure that you understand this safety information and consult with a healthcare professional if needed.

When taking this medication, you might experience some mild side effects such as nausea, constipation, drowsiness, or tiredness. These are generally not a cause for concern, but if they persist or worsen, it is advisable to consult your healthcare provider. Additionally, this medication may cause dizziness or low appetite in some individuals. Regularly monitoring your blood pressure is recommended, as the medication can cause it to rise. If you notice elevated blood pressure, discuss it with your healthcare provider, who may suggest ways to manage it.

Though rare, there are more serious side effects that necessitate immediate medical attention. These include symptoms of a severe allergic reaction, such as rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. Additionally, symptoms like blue fingers/toes or cold hands/feet should also prompt immediate consultation with a healthcare professional. While serious allergic reactions are uncommon, being aware of these signs ensures prompt treatment should they occur. Always keep in touch with your healthcare provider about any unusual symptoms you experience.