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The following safety and warning information is essential to understanding the potential risks and necessary precautions when using this medication. It is important to read these details thoroughly and discuss any concerns with your healthcare provider.

• Risk of Infection: Although Rebyota (fecal microbiota) is produced under stringent manufacturing controls to ensure it is free of harmful viruses and other microorganisms, its origin from human fecal matter means there is a potential risk for infection. If you experience a fever or symptoms indicative of an infection following administration, contact your healthcare provider immediately. Additionally, your healthcare provider will report such events to the manufacturer.

• Risk of Allergic Reaction: There is a possibility that Rebyota (fecal microbiota) could contain food allergens, due to its derivation from human fecal matter. For instance, if you have a severe allergy to kiwi and the donor of the fecal matter consumed kiwi, you might experience an allergic reaction. It is crucial to inform your healthcare provider of all known allergies prior to treatment. You will likely be monitored for any adverse reactions after receiving the medication.

There are no specific contraindications listed for this medication. Always consult your healthcare provider for personalized advice and further information.

When taking this medication, some individuals may experience mild side effects such as abdominal pain, diarrhea, bloating, gas, or nausea. These effects are common and generally not severe, but if they persist or worsen, it is advisable to consult with a healthcare provider for further guidance. Rest assured, many people using this medication do not experience serious side effects.

However, it is important to be aware of rare but serious allergic reactions. Symptoms of such reactions can include a rash, itching or swelling, particularly of the face, tongue, or throat, severe dizziness, or difficulty breathing. If you notice any of these symptoms, it is crucial to seek medical attention immediately.

Keep in mind that this is not an exhaustive list of possible side effects. Should you experience any effects not mentioned here, it is important to reach out to a healthcare professional for advice. Your well-being is important, and prompt communication with your healthcare provider ensures the best possible care.