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This medication, Rynex PSE (brompheniramine / pseudoephedrine), carries important safety information that requires careful consideration. It is essential to understand the potential risks and precautions associated with its use. If you have any doubts, please discuss them with your healthcare provider.

• Drowsiness: Rynex PSE may cause significant drowsiness, affecting your concentration, cognition, and reaction times. This effect can be amplified if you are over 65 years of age, consume alcohol, or use other medications that induce sleepiness, such as opioids, benzodiazepines, or sleep aids. Avoid driving or using machinery until you are certain of how this medication impacts you.

• Exacerbation of Health Conditions: Do not use Rynex PSE if you have been advised against it by your healthcare provider, as it can worsen existing conditions. Inform your provider of any current or past medical issues before starting this medication. Conditions of concern include glaucoma, heart disease, high blood pressure, thyroid issues, diabetes, respiratory problems, and urinary difficulties.

• Accidental Overdose: Rynex PSE contains brompheniramine and pseudoephedrine, which are also present in many other over-the-counter medications. Using multiple products with these ingredients, even topical ones, can lead to an overdose. Overdose symptoms may include high blood pressure, excessive drowsiness, dizziness, seizures, hallucinations, or even death.

• Contraindications: Avoid using this medication if it is intended as a sedative for children or if you have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days, as these situations present significant health risks.

Always prioritize safety and consult your healthcare provider if you have any questions or concerns regarding the use of this medication.

When using this medication, you may experience some common side effects that are generally mild and manageable. These include drowsiness, dizziness, dry mouth, headache, and an upset stomach. Constipation and trouble sleeping might also occur. Although these effects typically resolve on their own, if they persist or worsen, it's important to contact your healthcare provider for advice.

Some individuals may encounter other side effects, such as trouble urinating, weakness, or feelings of restlessness. You might also notice changes in blood pressure or experience changes in vision, like blurred or double vision. If these symptoms become bothersome or severe, consulting with your healthcare provider is recommended for further guidance.

In rare cases, more serious side effects can occur, necessitating immediate medical attention. These include mental or mood changes such as confusion or hallucinations, ringing in the ears, and significant difficulty with urination. Vision changes can also be serious, particularly if they're accompanied by a fast or irregular heartbeat or seizures. An allergic reaction, though rare, is serious and includes symptoms like rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing. If you notice any of these severe symptoms, seek medical help right away. Always report any unexpected side effects to your healthcare provider to ensure your safety.

Certain products and medications can interact with this drug. Topical antihistamines like diphenhydramine creams, ointments, or sprays may pose a risk. Moreover, combining this medication with MAO inhibitors could lead to a severe, potentially life-threatening interaction. It is crucial to avoid MAO inhibitors, including isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine, both during treatment and for two weeks prior. Consult your doctor for guidance on when to begin or discontinue this medication.

Additionally, inform your healthcare provider if you are using other products that cause drowsiness, such as opioid pain relievers (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety drugs (e.g., alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or other antihistamines (e.g., cetirizine, diphenhydramine).

Be sure to review the labels of all your medications, especially those for allergies or cold symptoms, as they may contain ingredients that induce drowsiness. Consult your pharmacist for advice on safe usage. Furthermore, this medication can interfere with certain medical or laboratory tests, including brain scans for Parkinson's disease, urine drug screenings, and allergy skin tests, potentially leading to inaccurate results. Ensure that all healthcare providers and lab personnel are aware of your medication usage.