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You might experience some mild side effects such as drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth, nose, or throat. These are generally manageable and may diminish as your body adjusts to the medication. To ease dry mouth, try sugarless hard candy, ice chips, or gum, and stay hydrated. Drinking plenty of fluids can also help prevent mucus from becoming too thick in your lungs, which can make breathing more difficult.

To minimize dizziness or lightheadedness, especially when standing up from a sitting or lying position, do so slowly. While these side effects are common, most individuals find them tolerable and they do not lead to serious health issues. However, if any mild side effects persist or worsen, consult your healthcare provider.

More serious side effects, although less common, require immediate medical attention. These include changes in mental state, such as confusion or hallucinations, ringing in the ears, tremors, difficulty urinating, weakness, easy bruising or bleeding, irregular heartbeat, or seizures. In rare cases, a severe allergic reaction may occur, characterized by rash, swelling, severe dizziness, or trouble breathing. If you experience these symptoms, seek medical help immediately.

This summary does not cover all possible side effects. If you notice others, contact your healthcare provider for guidance.

Be cautious when using this medication with certain MAO inhibitors, as it can lead to a severe and potentially life-threatening interaction. Do not take this medication alongside isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine. Additionally, you should generally avoid MAO inhibitors for two weeks before and after using this medication. Consult your doctor for specific guidance on when to begin or discontinue this medication.

Some other products that might interact with this medication include topical antihistamines like diphenhydramine cream, ointment, or spray, and rolapitant. Inform your healthcare provider if you are using other substances that can cause drowsiness, such as opioid pain or cough medications (e.g., codeine, hydrocodone), alcohol, marijuana (cannabis), medications for sleep or anxiety (e.g., alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or other antihistamines (e.g., cetirizine, diphenhydramine).

Always read the labels on your medications, including those for allergies or cold and cough, as they may contain ingredients that induce drowsiness. Speak with your pharmacist about how to safely use these products.

This medication might affect certain medical or laboratory tests, such as brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests, potentially leading to inaccurate results. Ensure that all lab personnel and your healthcare providers are aware that you are taking this medication.