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When taking this medication, be aware that side effects are generally rare. The most common side effects include darkening of the stools and tongue, which are harmless and should resolve once the medication is discontinued. It is important to stay hydrated, as persistent vomiting or diarrhea could lead to dehydration. Signs of dehydration include decreased urination, dry mouth, increased thirst, a rapid heartbeat, or dizziness. If you experience these, contact a healthcare professional immediately.

More serious side effects, though uncommon, require prompt medical attention. These include ringing in the ears or hearing loss. Additionally, in rare cases, the medication can cause severe bleeding in the stomach or intestines. Symptoms of this serious condition include persistent abdominal pain, vomit that resembles coffee grounds, and black, tarry, or bloody stools. If these symptoms occur, discontinue use and seek medical help right away.

Allergic reactions to this drug are very rare but can be severe. If you notice symptoms such as a rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, seek emergency medical assistance. Always monitor for any other unusual side effects and consult a healthcare provider if you experience anything concerning.

This medication can interact with certain drugs, including valproic acid, carbonic anhydrase inhibitors (such as acetazolamide), corticosteroids (like prednisone), dichlorphenamide, and methotrexate. Combining this medication with these can increase your risk of side effects. Additionally, when taken with drugs that also raise bleeding risk, such as anti-platelet medications like clopidogrel or blood thinners like dabigatran, enoxaparin, or warfarin, there is a higher chance of bleeding.

It's important to check all your medications, including over-the-counter options, as many contain pain relievers or fever reducers (NSAIDs like aspirin, ibuprofen, or naproxen) that are similar to this drug. Taking them together might increase the potential for side effects. However, if you've been advised by your doctor to take low-dose aspirin (81-162 mg daily) to prevent heart attack or stroke, continue doing so unless instructed otherwise by your doctor. Consult your doctor or pharmacist for detailed guidance.

This drug may affect certain medical or laboratory tests, such as intestinal x-rays using contrast dye, potentially leading to incorrect test results. Ensure that all medical staff and your healthcare providers are informed that you are using this medication.