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Bismuth Subsalicylate

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generic Bismatrol, Pepto-bismol, Stomach Relief, Eql Stomach Relief, Qc Pink Bismuth, Sm Stomach Relief, Soothe Maximum Strength, Soothe, Gnp Pink Bismuth, Eq Pink-bismuth, Peptic Relief, Cvs Anti-diarrheal, Ft Stomach Relief

Bismuth subsalicylate, commonly known as Pepto-Bismol, is a medication used to treat diarrhea, including travelers' diarrhea, and relieve symptoms of an upset stomach such as heartburn, nausea, gas, and indigestion. Suitable for adults and children over the age of 12, it is available over the counter in various forms, including chewable tablets and oral solutions. The medication works by slowing the movement of the stomach and intestines, reducing secretions in the gut, and aiding in the reabsorption of fluids and electrolytes. This action helps manage diarrhea and stomach irritation effectively. While bismuth subsalicylate is generally safe for occasional use, it should not be used to self-treat diarrhea if you have a fever or notice blood or mucus in stools, as these may indicate a more serious condition that requires medical attention. Additionally, this medication is used under medical supervision to treat stomach ulcers caused by the Helicobacter pylori bacteria, but it should not be used alone for this purpose due to potential bleeding risks associated with salicylates. Possible side effects include nausea, changes in taste, a dark-colored tongue, and black stool. Before using this medication or starting any treatment, consult with a healthcare professional to ensure its safety and efficacy for your personal condition. Always check the product label for ingredient updates or changes.
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1GM of 1, Bismuth Subsalicylate (1 Bottle)

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CVS

$19.46

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$2.00

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Bismuth Subsalicylate savings card

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Bismuth Subsalicylate dosage forms

The average cost for 1 Bottle of Bismuth Subsalicylate (generic Bismatrol, Pepto-bismol, Stomach Relief, Eql Stomach Relief, Qc Pink Bismuth, Sm Stomach Relief, Soothe Maximum Strength, Soothe, Gnp Pink Bismuth, Eq Pink-bismuth, Peptic Relief, Cvs Anti-diarrheal, Ft Stomach Relief) at 1GM of 1 is $1.01 with a free coupon. This is 7.99% off the average retail price of $12.64
DosageQuantityPrice fromPer unit
1GM of 11 Bottle$1.01$1.01

Bismuth Subsalicylate Warnings

This medication comes with important safety warnings and contraindications that you should be aware of before using it. It is essential to read these warnings carefully and discuss any concerns with your healthcare provider.

  • Reye's Syndrome in Children: Bismuth subsalicylate is linked to a rare but serious condition known as Reye's syndrome in children, particularly those recovering from flu-like symptoms or viral infections. Symptoms can start with vomiting, headache, and confusion, progressing to seizures or loss of consciousness. Avoid giving bismuth subsalicylate (Pepto-Bismol) to children with flu-related stomach upset. Always seek a healthcare provider's advice for appropriate medication options for sick children.

  • Salicylate Toxicity: Excessive intake of bismuth subsalicylate or other salicylate-containing products, such as aspirin or certain topical pain relief patches, can result in salicylate toxicity. Symptoms may include headache, dizziness, and ringing in the ears. Review the ingredients of all medications you are taking, including over-the-counter products, and inform your healthcare provider if you notice any symptoms of toxicity.

  • Allergic Reactions: Severe allergic reactions to bismuth subsalicylate, such as anaphylaxis, may occur. Symptoms include hives, difficulty breathing, and swelling of the lips or tongue. Seek emergency medical help immediately if these occur. Inform your healthcare provider if you have any known allergies to aspirin or other NSAIDs before starting this medication.

Contraindications: This medication should not be used if you have any of the following conditions, as it can pose serious health risks. Consult your healthcare provider if any of these apply to you:

  • Presence of a stomach ulcer
  • Bleeding disorders
  • Bloody or black stools
  • Allergy to salicylates or concurrent use of other salicylate-containing medications (e.g., aspirin)

Adhering to these warnings and contraindications is crucial for safe usage of the medication. Always consult with your healthcare provider for personalized advice.

Bismuth Subsalicylate Side Effects

Common side effects:

  • Nausea
  • Bitter taste in the mouth
  • Diarrhea
  • Dark-colored stools

Less common but important to monitor:

  • Tiredness
  • Mood changes
  • Dark-colored tongue or teeth
  • Ringing in the ears

Serious side effects:

  • Severe allergic reactions (e.g., trouble breathing, blisters, hives, swelling of the tongue or lips)
  • Salicylate toxicity (e.g., headache, dizziness, confusion, ringing in the ears, trouble breathing, nausea, vomiting, stomach pain)

Bismuth Subsalicylate Interactions

Some products that may interact with this drug are: valproic acid, carbonic anhydrase inhibitors (such as acetazolamide), corticosteroids (such as prednisone), dichlorphenamide, methotrexate. This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others. Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that are similar to this drug and, if taken together, may increase your risk for side effects. However, if your doctor has told you to take low-dose aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should keep taking the aspirin unless your doctor tells you not to. Ask your doctor or pharmacist for more details. This medication may interfere with certain medical/lab tests (such as x-rays of the intestines using contrast dye), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Bismuth Subsalicylate FAQs
What is the difference between Pepto-Bismol and bismuth?

Pepto-Bismol is an over-the-counter medication that contains bismuth subsalicylate as its active ingredient. Bismuth subsalicylate is a compound that provides relief from symptoms such as nausea, heartburn, indigestion, upset stomach, and diarrhea. While bismuth is a chemical element, in the context of Pepto-Bismol, it is part of the bismuth subsalicylate compound. Therefore, Pepto-Bismol is a specific formulation that includes bismuth subsalicylate, along with other inactive ingredients, to treat gastrointestinal symptoms.

When taking bismuth subsalicylate, it is important to avoid consuming alcohol, as it can increase the risk of stomach bleeding. Additionally, one should avoid taking other salicylate-containing medications, such as aspirin, to prevent an overdose of salicylates. It is also advisable to avoid dairy products and antacids, as they can interfere with the effectiveness of the medication. If the individual is taking other medications, they should consult with a healthcare provider to ensure there are no interactions.

France banned Pepto-Bismol due to concerns about its active ingredient, bismuth subsalicylate, which is chemically related to aspirin. The concern is primarily related to the risk of Reye's syndrome, a rare but serious condition that can occur in children and teenagers recovering from viral infections. Additionally, regulatory differences and safety evaluations can vary between countries, leading to such decisions.

Bismuth subsalicylate should not be taken with other salicylates, such as aspirin, to avoid the risk of salicylate toxicity. It should also be used cautiously with anticoagulants like warfarin, as it may increase the risk of bleeding. Additionally, it is advisable to avoid taking it with tetracycline antibiotics, as it can interfere with their absorption. Always consult a healthcare provider before combining medications.

Bismuth helps alleviate stomach discomfort by coating the stomach lining and protecting it from irritants. It also has mild antibacterial properties that can help reduce inflammation and treat certain infections, such as Helicobacter pylori, which is associated with ulcers. Additionally, bismuth can help reduce diarrhea by decreasing fluid secretion in the intestines.