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When using this medication, it is important to be aware of potential interactions and precautions to ensure your safety. Below are key points to consider:

• Avoid MAO Inhibitors: Do not use this medication in combination with certain monoamine oxidase (MAO) inhibitors, as this can lead to a serious and potentially life-threatening reaction. The MAO inhibitors to avoid include isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine. Additionally, most MAO inhibitors should not be taken for two weeks before starting this treatment. Consult with your doctor regarding the appropriate timing for starting or stopping this medication.

• Potential Drug Interactions: Be cautious of interactions with other medications, such as rolapitant. Always review your current medications with your healthcare provider to prevent harmful interactions.

• Check Medication Labels: Guaifenesin and dextromethorphan are ingredients that can be found in both prescription and over-the-counter products. Ensure you are not using multiple products that contain these ingredients simultaneously, as this can lead to excessive dosing.

• Lab Test Interference: Guaifenesin may affect certain laboratory tests, such as those measuring urine levels of specific acids, which could result in incorrect test outcomes. It is crucial to inform all healthcare professionals and laboratory staff that you are taking this medication to avoid misinterpretation of test results.

By following these guidelines and communicating openly with your healthcare provider, you can help minimize risks and ensure effective treatment.

It is important to be aware that using certain MAO inhibitors with this medication can lead to a severe, potentially life-threatening interaction. You should avoid taking medications such as isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while on this treatment. Additionally, most MAO inhibitors should not be used for two weeks prior to starting this medication. Consult your doctor for guidance on when to begin or discontinue this treatment.

Another drug that may interact with this medication is rolapitant.

Both Guaifenesin and dextromethorphan are found in prescription and over-the-counter products, so it's crucial to check all your medications to ensure you're not taking more than one containing these substances. Additionally, guaifenesin can affect certain laboratory tests, potentially leading to inaccurate results. Inform your healthcare providers and lab technicians if you are using this drug.