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Before using this medication, it's important to be aware of the potential risks and necessary precautions to ensure your safety. The following points highlight key safety information you should consider and discuss with your healthcare provider.

• Cigarette Smoking and Heart Risks: If you are a smoker, especially if you are 35 years or older, using hormonal contraceptives like Yasmin can significantly increase your risk of serious cardiovascular events such as stroke, heart attack, and blood clots. It's crucial to explore safer contraceptive options if you smoke.

• Blood Clots and Stroke: Yasmin may elevate the risk of blood clots in various parts of your body, including the lungs (pulmonary embolism), legs (deep vein thrombosis), brain (stroke), and heart (heart attack). Immediate medical attention is necessary if you notice symptoms of blood clots. Higher risk factors include being over 35 and smoking, recent surgery, bed rest, starting Yasmin soon after childbirth, high blood pressure, obesity, or diabetes.

• Cancer Risks: There is a potential increase in the risk of breast and cervical cancer with long-term use of Yasmin. This risk is particularly relevant for those with a history of breast cancer or prolonged use of combined oral contraceptives (COCs).

• Liver Concerns: Although rare, Yasmin can cause liver issues, including damage and tumors, especially in those with pre-existing liver conditions or using COCs with high estrogen levels. Seek medical advice if you experience symptoms like fatigue, stomach pain, or jaundice.

• Blood Pressure: Yasmin may cause an increase in blood pressure. Regular monitoring is advised, and if you have uncontrolled high blood pressure, discuss alternative options with your healthcare provider.

• Blood Sugar and Lipid Levels: Yasmin might raise blood sugar and fat levels in the blood, which is a concern for individuals with diabetes or high triglyceride levels. Regular medical check-ups are important to monitor these changes.

• Headaches: Report any severe or recurring headaches, especially migraines, to your healthcare provider as they may necessitate stopping the medication.

• Depression: Notify your provider if you experience new or worsening symptoms of depression. In severe cases, discontinuation of Yasmin may be necessary.

• Drug Interactions: Certain medications can affect how Yasmin works, potentially reducing its effectiveness or increasing side effects. It's essential to inform your provider about all medications you are taking.

• High Potassium Levels: Yasmin contains drospirenone, which can increase potassium levels. This is particularly important if you have kidney, liver, or adrenal problems or are taking other medications that affect potassium.

In case of any contraindications such as existing kidney, liver, or adrenal gland issues, being over 35 and smoking, blood clots risk, abnormal uterine bleeding, certain heart conditions, uncontrolled high blood pressure or diabetes, pregnancy, breast cancer, specific types of headaches, or current treatment with medications like Viekira Pak, consult your healthcare provider before using this medication.

When taking this medication, you may experience some common side effects such as nausea, vomiting, headaches, bloating, breast tenderness, and fluid retention, which can lead to swelling in the ankles or feet. It's not uncommon to notice changes in weight or experience premenstrual syndrome (PMS). You might also encounter vaginal bleeding between periods or missed/irregular periods, especially during the initial months of usage. While these effects are usually mild, if they persist or worsen, it's advisable to consult a healthcare professional.

Keep in mind that this medication can raise blood pressure, so monitoring your levels regularly is important. If you notice high readings, inform your doctor. Mood changes, including depression, can also occur, so it's vital to stay attentive to your mental health.

Severe side effects, although rare, require immediate medical attention. These include symptoms indicative of blood clots, such as chest pain, shortness of breath, sudden dizziness, or severe headaches. Signs of a stroke or heart attack, like weakness on one side of the body or confusion, are critical and necessitate urgent care. Additionally, symptoms of liver issues, such as yellowing of the skin or eyes, and very serious allergic reactions, such as rash or trouble breathing, warrant prompt medical evaluation.

Lastly, if you notice any unusual changes in vaginal bleeding or experience severe abdominal pain, seek medical advice. Always remain vigilant for these symptoms and contact a healthcare provider if you experience any side effects, especially those that are severe or unexpected.

When using Yasmin, it's important to be aware of potential interactions with other drugs. Inform your healthcare provider about all medications, supplements, and herbal products you are taking. Some drugs should not be combined with Yasmin, such as boceprevir, dasabuvir, ombitasvir, paritaprevir, Ritonavir, and Tranexamic Acid. These combinations are usually avoided, or your doctor may adjust your treatment.

In certain cases, using Yasmin with medications like amifampridine, Amoxicillin, Carbamazepine, Fosamprenavir, griseofulvin, Modafinil, Rifampin, St. John's wort, and Topiramate may lead to decreased effectiveness of hormonal birth control, increasing the risk of pregnancy. If you are prescribed any of these, your doctor might adjust dosages or suggest additional contraceptive methods.

Some medications, like Amitriptyline, Atazanavir, Diazepam, and Warfarin, may increase the risk of side effects when taken with Yasmin. Your healthcare provider may modify how you use either of the medications to manage these risks.

Additionally, Yasmin can affect lab test results, potentially leading to inaccuracies. Ensure all medical personnel are aware that you are taking this medication. Always consult your doctor before starting any new medication, and inform them of any unusual symptoms such as unexpected bleeding, which might indicate that your birth control is not functioning properly.