Tetrabenazine Coupons & Discount Card – Guaranteed Prices from $47.47
generic Xenazine
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12.5MG, Tetrabenazine (30 Tablets)
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$47.47
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Tetrabenazine dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 25MG | 30 Tablets | $51.62 | $1.72 |
| 12.5MG | 30 Tablets | $59.8 | $1.99 |
Tetrabenazine Warnings
Tetrabenazine, also known as Xenazine, is a medication that requires careful consideration of its safety and potential risks. Below is important information you need to know before using this medication. Please ensure to discuss any concerns with your healthcare provider.
Depression and Suicidal Thoughts: Tetrabenazine may increase the risk of depression and suicidal thoughts, particularly in individuals with Huntington's disease. It is crucial for healthcare providers to monitor patients for these symptoms throughout treatment. If you or those around you notice any signs such as worsening depression, suicidal thoughts, anxiety, panic attacks, or changes in behavior, contact your healthcare provider immediately. Discontinuation of the medication may be necessary if symptoms persist.
Huntington's Disease Symptoms: Tetrabenazine can potentially worsen some symptoms of Huntington's disease, such as mood changes, cognitive difficulties, and muscle stiffness. Regular assessments by your healthcare provider are essential to determine the medication's safety and effectiveness. Adjustments in dosage or a temporary discontinuation of the medication may be needed based on symptom evaluation.
Genetic Testing for Dosage: For those who require more than 50 mg of tetrabenazine daily, genetic testing might be necessary to assess how your body metabolizes the drug. Based on the test results, your dosage may be adjusted to improve treatment effectiveness.
Neuroleptic Malignant Syndrome (NMS): This medication can cause a rare but serious condition called NMS, characterized by high fever, muscle stiffness, confusion, and irregular heartbeat. The risk increases with the use of other medications such as antipsychotics. Immediate medical attention is required if symptoms occur.
Movement Disorders (Parkinsonism): Tetrabenazine may cause restlessness, agitation, or a condition known as akathisia. If these symptoms arise, consult your healthcare provider.
Heart Rhythm Abnormalities (QT Prolongation): Although rare, tetrabenazine can lead to QT prolongation, affecting heart rhythms. Those with low heart rates, low potassium or magnesium levels, or those taking other QT-prolonging drugs are at higher risk. Any symptoms like chest pain, fainting, or shortness of breath should be treated as emergencies.
High Prolactin Levels: The drug may increase prolactin levels, potentially leading to breast growth or milk production in both sexes, and may affect bone density and sexual interest. Notify your healthcare provider if you experience these symptoms.
Contraindications: Do not use tetrabenazine if you have untreated or unresolved depression, suicidal thoughts, liver failure, or if you are taking MAOIs or other similar medications such as Austedo or Ingrezza. Always consult your healthcare provider before starting or stopping any medication.
Tetrabenazine Side Effects
Common side effects:
- drowsiness
- trouble sleeping
- tiredness
- dizziness
- nausea
- vomiting
- mild mood changes such as anxiety or irritability
Less common but important to monitor:
- headache
- slurred speech
- unsteady gait
- shortness of breath
- low appetite
- feelings of restlessness
- increase in depression symptoms
Serious side effects:
- neuroleptic malignant syndrome symptoms (high fever, muscle stiffness, severe confusion, abnormal heart rhythms)
- severe mood changes
- suicidal thoughts
- chest pain
- difficulty breathing
- serious allergic reactions (rash, swelling, trouble breathing)
Tetrabenazine Interactions
Interactions with high risk of serious adverse effects and should be avoided:
- MAO inhibitors (isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine)
- Deutetrabenazine
- Bepridil
- Brofaromine
- Cisapride
- Clorgyline
- Dronedarone
- Furazolidone
- Iproniazid
- Lazabemide
- Mesoridazine
- Nialamide
- Pargyline
- Pimozide
- Piperaquine
- Reserpine
- Saquinavir
- Sparfloxacin
- Terfenadine
- Thioridazine
- Toloxatone
- Ziprasidone
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Valbenazine
- Acecainide
- Ajmaline
- Alfuzosin
- Amiodarone
- Amisulpride
- Amitriptyline
- Amoxapine
- Anagrelide
- Apomorphine
- Aripiprazole
- Aripiprazole Lauroxil
- Arsenic Trioxide
- Artemether
- Asenapine
- Astemizole
- Azimilide
- Azithromycin
- Bedaquiline
- Bretylium
- Buprenorphine
- Buserelin
- Ceritinib
- Chloroquine
- Chlorpromazine
- Ciprofloxacin
- Citalopram
- Clarithromycin
- Clofazimine
- Clomipramine
- Clozapine
- Crizotinib
- Cyclobenzaprine
- Dabrafenib
- Dasatinib
- Degarelix
- Delamanid
- Desipramine
- Deslorelin
- Disopyramide
- Dofetilide
- Dolasetron
- Domperidone
- Donepezil
- Droperidol
- Efavirenz
- Encorafenib
- Entrectinib
- Erythromycin
- Escitalopram
- Fingolimod
- Flecainide
- Fluconazole
- Fluoxetine
- Formoterol
- Foscarnet
- Fostemsavir
- Gatifloxacin
- Gemifloxacin
- Glasdegib
- Gonadorelin
- Goserelin
- Granisetron
- Halofantrine
- Haloperidol
- Histrelin
- Hydroquinidine
- Hydroxychloroquine
- Hydroxyzine
- Ibutilide
- Iloperidone
- Imipramine
- Inotuzumab Ozogamicin
- Iobenguane I 131
- Ivabradine
- Ivosidenib
- Ketoconazole
- Lapatinib
- Lefamulin
- Lenvatinib
- Levofloxacin
- Lofexidine
- Lopinavir
- Lumefantrine
- Macimorelin
- Mefloquine
- Methadone
- Metronidazole
- Mifepristone
- Moxifloxacin
- Nafarelin
- Nilotinib
- Norfloxacin
- Nortriptyline
- Octreotide
- Ofloxacin
- Olanzapine
- Ondansetron
- Osilodrostat
- Osimertinib
- Oxaliplatin
- Ozanimod
- Paliperidone
- Panobinostat
- Pasireotide
- Pazopanib
- Pimavanserin
- Pirmenol
- Pitolisant
- Ponesimod
- Posaconazole
- Prajmaline
- Procainamide
- Prochlorperazine
- Promethazine
- Propafenone
- Protriptyline
- Quetiapine
- Quinidine
- Quinine
- Ranolazine
- Ribociclib
- Risperidone
- Selpercatinib
- Sematilide
- Sertraline
- Sevoflurane
- Siponimod
- Sodium Phosphate
- Solifenacin
- Sorafenib
- Sotalol
- Sulpiride
- Sunitinib
- Tacrolimus
- Tedisamil
- Telavancin
- Telithromycin
- Toremifene
- Trazodone
- Triclabendazole
- Trifluoperazine
- Trimipramine
- Triptorelin
- Vandetanib
- Vardenafil
- Vemurafenib
- Vinflunine
- Voclosporin
- Voriconazole
- Zuclopenthixol
Interactions with low risk that usually do not require a change in therapy:
- Paroxetine
Is tetrabenazine an antipsychotic?
Tetrabenazine is not classified as an antipsychotic. It is a medication primarily used to treat movement disorders, such as those associated with Huntington's disease.
Who should not use tetrabenazine?
Tetrabenazine should not be used by individuals with untreated or inadequately treated depression, those with suicidal thoughts, or those with hepatic impairment. It is also contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or reserpine. Additionally, individuals with a known hypersensitivity to tetrabenazine or any of its components should avoid using it. It is important for patients to consult with their healthcare provider to determine if tetrabenazine is appropriate for their condition.
What drug group is tetrabenazine?
Tetrabenazine belongs to the drug group known as vesicular monoamine transporter 2 (VMAT2) inhibitors.
Is Austedo the same as tetrabenazine?
Austedo and tetrabenazine are not the same, but they are related. Both are used to treat movement disorders, such as chorea associated with Huntington's disease. Austedo contains the active ingredient deutetrabenazine, which is a deuterated form of tetrabenazine. This modification allows Austedo to have a longer half-life and potentially fewer side effects compared to tetrabenazine.
What medication is like Austedo?
A medication similar to Austedo is tetrabenazine. Both are used to treat chorea associated with Huntington's disease. Another alternative is valbenazine, which is used for tardive dyskinesia, a condition Austedo also treats. These medications work by affecting certain neurotransmitters in the brain.