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This document outlines critical safety and warning information for the medication TobraDex (tobramycin / dexamethasone). It is essential to follow these guidelines and consult your healthcare provider with any questions or concerns.

• Application: TobraDex is intended for use on the surface of the eye only. Avoid applying it in the mouth, nose, or other body parts, and do not inject it into any part of the eye.

• Increased Eye Pressure: Long-term use of steroid-containing eye medications like TobraDex can elevate eye pressure, potentially leading to eye damage and vision issues. Patients with glaucoma or high eye pressure should discuss the risks and benefits with their healthcare provider. Risks are heightened with usage beyond 10 days and a history of glaucoma.

• Infection Risks: Prolonged use of TobraDex may increase the likelihood of developing new eye infections, including fungal or bacterial types. It should not be used for viral eye infections, as it may exacerbate these conditions. Contact a healthcare provider if you experience eye pain, redness, blurred vision, sensitivity to light, or watery discharge, especially if symptoms persist after a few days.

• Potential Eye Damage: Extended use of TobraDex may cause thinning of the cornea or eye surface, potentially leading to damage. It can also contribute to cataract formation. Immediate medical attention is advised if symptoms such as vision loss, blurry vision, or increased eye watering occur. This risk is particularly pertinent for individuals with a history of cataracts or prolonged use of the medication.

• Allergic Reactions: Inform your primary care provider if you have allergies to similar antibiotics, such as gentamicin (Gentak), as there is a chance of an allergic reaction to TobraDex.

Contraindications:

• Viral Eye Infections: Do not use TobraDex if you have eye infections caused by viruses like varicella or herpes.

• Bacterial or Fungal Eye Infections: Avoid using this medication for mycobacterial or fungal eye infections.

In case of an overdose or severe reaction, seek emergency medical assistance promptly. Always consult your healthcare provider for further guidance tailored to your specific health needs.

When using this medication, you may experience some common side effects such as temporary blurred vision, redness of the eyes, and discomfort. Additionally, your eyelids might feel itchy or appear swollen. These effects are generally mild, but if they persist or worsen, it’s advisable to consult a healthcare provider for guidance.

It's important to be aware of more serious side effects, although they are rare. Prolonged use of this medication can lead to new eye issues, like fungal infections, glaucoma, or cataracts. If you notice new or worsening eye symptoms, such as discharge, swelling, or changes in vision, it is crucial to seek medical advice promptly.

In very rare cases, a serious allergic reaction can occur. Look out for symptoms like rash, severe itching, especially around the face, tongue, or throat, intense dizziness, or difficulty breathing. Immediate medical attention is necessary if you experience any of these symptoms.

Additionally, some users have reported slower healing of the eye and eye pain, especially when touching or moving the eye. Should you encounter these effects, particularly if they are severe, contacting a healthcare professional is essential. Remember, this is not an exhaustive list of side effects, so any other unusual symptoms should also be discussed with your healthcare provider.