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This safety and warning information is crucial for understanding the potential risks and necessary precautions associated with the use of Zylet (loteprednol / tobramycin) eye drops. Please read it thoroughly and consult your healthcare provider with any concerns.

• Intended Use: Zylet is designed solely for application to the eyes. Do not apply it to any other part of your body.

• Risk of Eye Infections and Problems: Prolonged use of Zylet may increase the likelihood of developing new or worsening eye infections, as well as issues such as glaucoma, cataracts, and vision impairments. Regular eye examinations are recommended if using Zylet for an extended period (10 days or more). Notify your doctor if you experience changes in vision, eye pain, or new symptoms of an eye infection. Risks are heightened for those with a history of glaucoma, cataracts, viral eye infections (including herpes simplex), or recent corneal surgery.

• Delayed Healing Post-Eye Surgery: Steroid eye drops like Zylet may slow down the healing process following cataract surgery or similar procedures. Inform your healthcare provider if you have recently undergone cataract or other eye surgeries.

• Potential Eye Damage: Zylet can potentially cause eye injury, such as corneal thinning. Contact your doctor immediately if you experience vision changes, eye pain, or watery eyes, as a check-up may be necessary.

• Contact Lenses: Avoid wearing contact lenses while using Zylet, as the preservative in the medication can damage them.

• Allergic Reactions: If you are allergic to aminoglycoside antibiotics like tobramycin, you might also be allergic to Zylet. Severe allergic reactions can be life-threatening and may include symptoms such as facial swelling, dizziness, or anaphylaxis. Seek medical attention right away if you notice hives, rash, swelling of the lips or tongue, or difficulty breathing.

• Contraindications: Zylet should not be used for viral, fungal, or mycobacterial infections of the eye, as it could pose significant health risks. Discuss with your healthcare provider if any of these conditions apply to you.

When using this medication, some common side effects include a temporary burning or stinging sensation in the eyes, which typically lasts for a minute or two. In some cases, redness and swelling of the cornea, headaches, increased eye pressure, and eye discomfort such as sensitivity to light or itchiness may occur. These effects are usually mild, but if they persist or worsen, it's important to consult your healthcare provider for further guidance.

In rare instances, the medication can lead to more serious side effects, such as new or worsening eye symptoms, including discharge, redness, swelling, or vision problems. If you experience any of these, or if you notice any eye pain, it's crucial to seek immediate medical attention. Additionally, prolonged use of this medication may increase the risk of developing other eye issues like glaucoma or cataracts.

A very serious allergic reaction to this medication is uncommon, but requires urgent medical intervention. Signs of an allergic reaction include hives, severe dizziness, trouble breathing, or swelling of the face, tongue, or throat. If any of these symptoms occur, seek emergency medical care promptly. Always remain observant for any unusual effects and communicate with your healthcare provider to ensure your safety while using this medication.