Tolcapone

Drug Details

Tolcapone, marketed as Tasmar, is an oral medication used as an add-on to enhance the treatment of Parkinson's disease, particularly when carbidopa/levodopa alone does not adequately manage symptoms. It belongs to a group of medications known as catechol-O-methyltransferase (COMT) inhibitors. Tolcapone works by inhibiting the COMT enzyme, which helps maintain stable levels of levodopa in the body. This action prevents the premature breakdown of levodopa, allowing it to remain in the system longer, thereby reducing the risk of symptoms returning or worsening between doses. This medication should be used under the guidance of a healthcare professional.