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Bupropion hydrochloride (HCL) is prescribed as an antidepressant and is also utilized to aid smoking cessation. While it offers significant benefits, including reducing suicidal thoughts and attempts, there are some risks involved. This medication may lead to new or worsening symptoms of depression or other mental health disorders, especially in individuals under 25 years of age.

To ensure safe use of bupropion, please consider the following points:

• Discuss with your doctor the potential benefits and risks associated with antidepressant use, even if prescribed for conditions unrelated to mental health.
• Immediately inform your doctor if you observe any new or worsening symptoms of depression, changes in behavior, or other mental health changes. This includes suicidal thoughts, anxiety, panic attacks, sleep disturbances, irritability, anger, impulsive actions, severe restlessness, or unusually rapid speech.
• Pay close attention to these symptoms when beginning treatment with a new antidepressant or adjusting the dosage.
• If you are taking bupropion to help quit smoking and experience any of the symptoms mentioned, stop taking the medication and contact your healthcare provider immediately.
• Similarly, if you notice these symptoms after discontinuing bupropion, notify your doctor without delay.

These precautions are vital to ensure your safety and optimize the therapeutic effects of bupropion.

You may experience some common side effects such as dry mouth, sore throat, dizziness, nausea, vomiting, ringing in the ears, headache, decreased appetite, weight loss, constipation, trouble sleeping, increased sweating, or shaking. These are generally mild, but if they persist or worsen, it is advisable to consult your healthcare provider.

Occasionally, you might notice an empty tablet shell in your stool; this is harmless as the medication has already been absorbed. It is important to monitor your blood pressure while on this medication, as it can cause an increase. Contact your healthcare provider if you observe elevated blood pressure readings.

Be aware of more serious side effects, including an irregular heartbeat, changes in mood or behavior, significant weight changes, or memory loss. Immediate medical attention is crucial if you experience seizures, eye pain, vision changes, or a severe allergic reaction, which could manifest as a rash, swelling, or difficulty breathing. Although these severe reactions are rare, they require prompt care. Always report any unexpected side effects to your healthcare provider to ensure your safety.