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Tenapanor, marketed under the name Xphozah, is a prescribed medication designed to reduce elevated blood phosphate levels in adults with chronic kidney disease who are undergoing dialysis. This medication is particularly useful as an additional treatment for patients who have not responded well to or are unable to take phosphate binders. It is the first FDA-approved phosphate absorption inhibitor of its kind and functions by blocking a protein in your gut, sodium/hydrogen exchanger 3 (NHE3), to prevent phosphate absorption from food into the bloodstream. By lowering phosphate levels, Tenapanor helps maintain bone strength, prevents harmful mineral buildup, and may reduce the risk of heart disease and strokes associated with high phosphate levels. This medication is administered orally in tablet form, twice daily before breakfast and dinner. While a common side effect is diarrhea, it typically subsides with continued use. It is important to note that Tenapanor should not be used by children under six years of age due to the risk of serious dehydration. Always consult with a healthcare professional before starting any medication to ensure it is safe and effective for your individual health needs.