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When taking Aristada (aripiprazole lauroxil), it is important to be aware of several safety considerations and potential risks associated with its use. Below is a summary of key warnings and precautions:

• Increased Risk in Dementia-Related Psychosis: Older adults with dementia-related psychosis should not use Aristada, as it may lead to fatal outcomes such as heart problems, stroke, or infections. Consult your healthcare provider if you or a loved one has dementia before starting treatment.

• Neuroleptic Malignant Syndrome (NMS): This medication can cause a rare but severe condition known as NMS, characterized by high fever, muscle stiffness, confusion, and irregular heartbeat. Seek immediate medical attention if these symptoms occur.

• Tardive Dyskinesia: Aristada may result in uncontrollable and potentially permanent muscle movements (tardive dyskinesia). To minimize the risk, use the lowest effective dose. Report any unusual movements to your healthcare provider promptly.

• Metabolic Changes: The medication may lead to elevated blood sugar, cholesterol, and weight gain, which can be dangerous. Inform your provider if you experience symptoms like increased hunger, thirst, frequent urination, stomach pain, weakness, or fruity-smelling breath, especially if you have a history of diabetes or high cholesterol.

• Impulsive Behaviors: Aristada can affect impulse control, potentially leading to harmful behaviors such as gambling or excessive eating. Notify your provider if you observe such changes in behavior.

• Increased Fall Risk: The drug can cause sleepiness, dizziness, and sudden drops in blood pressure, increasing the risk of falls. Stand up slowly, particularly when beginning treatment or increasing your dose, and discuss persistent dizziness with your provider.

• Infection Risk: Aristada may lower white blood cell counts, raising the risk of serious infections. Regular lab work may be necessary, and you should report symptoms like fever or sore throat to your provider.

• Seizure Risk: There is an increased likelihood of seizures with Aristada, particularly if you have a seizure history or a related medical condition. Discuss any such risks with your healthcare provider before starting the medication.

It is crucial to discuss all potential risks and benefits of Aristada with your healthcare provider, especially if you have pre-existing health conditions or are taking other medications. In case of overdose or severe side effects, seek emergency medical assistance immediately.

When taking this medication, some common side effects you may experience include dizziness, lightheadedness, drowsiness, tiredness, blurred vision, and weight gain. These are generally mild but should be discussed with a healthcare provider if they persist or worsen. It's important to rise slowly from sitting or lying positions to minimize the risk of falls due to dizziness or lightheadedness.

Occasionally, you might notice tremors, redness, pain, or swelling at the injection site, as well as experiencing restlessness or trouble sleeping. If any unusual or uncontrollable muscle movements, such as muscle spasms, occur, consult your healthcare provider.

While serious side effects are rare, they require immediate medical attention. These include neuroleptic malignant syndrome, characterized by high fever, sweating, confusion, and stiffness. Additionally, impulse-control issues, such as compulsive gambling or eating, as well as extremely high blood sugar levels, may occur. Symptoms of high blood sugar include increased thirst or hunger, frequent urination, and fruity-smelling breath.

Tardive dyskinesia, a rare condition involving involuntary movements like tongue protrusion or lip smacking, is another potential concern. Seizures may also occur and should be treated urgently. Allergic reactions to this medication are very rare but require immediate medical help if symptoms like rash, swelling, or difficulty breathing arise.

This medication's side effects can vary, and it's crucial to maintain open communication with your healthcare provider to manage them effectively.

When taking Aristada (aripiprazole lauroxil), it's important to be aware of potential drug interactions. Inform your doctor and pharmacist about all medications and supplements you're currently using, including prescription, over-the-counter, vitamins, and herbal products.

One key medication that can interact with Aristada is Metoclopramide. Additionally, be cautious if you're using products that cause drowsiness, as they may enhance this effect. These include opioid pain or cough relievers like codeine and hydrocodone, alcohol, marijuana, sleep or anxiety medications such as Alprazolam and Lorazepam, muscle relaxants like Carisoprodol and Cyclobenzaprine, and antihistamines such as Cetirizine and diphenhydramine. Always check the labels of your medications for ingredients that can cause drowsiness and consult your pharmacist for safe usage advice.

Furthermore, there are medications that are generally not recommended to be used with Aristada, such as Bepridil, Bromopride, Cisapride, Dronedarone, Fluconazole, Ketoconazole, Mesoridazine, Metoclopramide, Pimozide, Piperaquine, Posaconazole, Saquinavir, Sparfloxacin, Terfenadine, Thioridazine, and Ziprasidone. If necessary, your doctor might adjust the dose or frequency of these medications.

There are also drugs that might be used with caution, requiring dose adjustments or monitoring, including but not limited to Alprazolam, Amitriptyline, Bupropion, Citalopram, Codeine, Cyclobenzaprine, Fentanyl, Hydrocodone, Methadone, Morphine, Oxycodone, Sertraline, and Tramadol. Always discuss with your healthcare provider before combining Aristada with any other medications.