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This safety and warning information outlines critical precautions for the use of bismuth subsalicylate (commonly known as Pepto-Bismol). Please carefully consider these points and discuss any concerns with your healthcare provider.

• Reye's Syndrome in Children: Bismuth subsalicylate is associated with Reye's syndrome, a rare but serious condition in children, particularly those recovering from viral infections such as the flu or chickenpox. Symptoms begin with vomiting, headache, and confusion, potentially escalating to seizures and unconsciousness. Avoid giving this medication to a child with flu-related upset stomach. Consult a healthcare provider for suitable alternatives for sick children.

• Salicylate Toxicity: Overconsumption of bismuth subsalicylate or other salicylate-containing products, like aspirin or certain pain relief patches, can result in salicylate toxicity. Be vigilant about the ingredients in your medications, including over-the-counter options. Symptoms of toxicity include headache, dizziness, and tinnitus (ringing in the ears). Inform your healthcare provider if these symptoms occur.

• Allergic Reactions: Severe allergic reactions to bismuth subsalicylate are possible, including anaphylaxis. Seek emergency medical assistance if you experience hives, difficulty breathing, or swelling of the lips or tongue. Notify your healthcare provider of any known allergies to aspirin or NSAIDs before starting this medication.

Contraindications: Avoid using bismuth subsalicylate if you have any of the following conditions, as it may pose significant health risks:

• Stomach ulcers
• Bleeding disorders
• Bloody or black stools
• Allergies to or concurrent use of other medications containing salicylates (e.g., aspirin)

Consult with your healthcare provider to ensure safe use of this medication.

When taking this medication, some people commonly experience mild side effects such as nausea, a bitter taste in the mouth, diarrhea, and dark-colored stools. Generally, these are not serious, but if they continue or cause concern, it's advisable to speak with a healthcare professional.

Other side effects that have been reported include tiredness, mood changes, dark-colored tongue or teeth, and ringing in the ears. While these effects are not typically severe, it is important to monitor them and consult a healthcare provider if they become bothersome.

In rare instances, more serious side effects can occur, requiring immediate medical attention. These include severe allergic reactions, which may present as trouble breathing, blisters, hives, or swelling of the tongue or lips. Additionally, signs of salicylate toxicity, such as headache, dizziness, confusion, ringing in the ears, trouble breathing, nausea, vomiting, and stomach pain, are critical and necessitate urgent care. Always stay attentive to how your body responds to the medication and act swiftly if severe symptoms arise.