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The following safety information outlines crucial warnings associated with the use of bromfenac eye drops. It is essential to review these details and consult with your healthcare provider if you have any concerns or questions.

• Allergic Reactions: Bromfenac may contain sulfites, which could trigger an allergic reaction, particularly in individuals with asthma or a known sulfite allergy. Avoid using bromfenac if you have these sensitivities.

• Healing Delays: Bromfenac can slow down eye healing, especially if used concurrently with steroid eye drops such as prednisolone or loteprednol. Consult your eye specialist if you are worried about your healing process.

• Increased Bleeding Risk: There is a heightened risk of bleeding in the eye tissue following surgery when using bromfenac. Inform your doctor if you have a history of bleeding disorders or are taking blood-thinning medications. Seek medical advice if you observe blood spots in your eyes, particularly after surgery.

• Corneal Issues: The use of bromfenac can lead to complications in the cornea, including inflammation, thinning, injury, or ulcers. These issues can potentially impair vision. Notify your healthcare provider if you have a history of corneal problems, dry eyes, multiple or complex eye surgeries, rheumatoid arthritis, diabetes, or long-term bromfenac use.

• Contact Lens Use: Remove contact lenses before applying bromfenac drops, as the preservative in the drops can damage lenses. Wait at least 10 minutes after application before reinserting your contact lenses.

Please ensure you understand these warnings and take appropriate precautions when using bromfenac eye drops.

When using this medication, some common side effects might occur, though they are generally mild and temporary. You may experience irritation, burning, or stinging sensations in the eye, blurred vision, watery eyes, or headaches. These effects should not cause alarm unless they persist or worsen, in which case consulting your healthcare provider is advised.

More serious side effects, though rare, demand immediate medical attention. These include severe pain or redness in the eye, sensitivity to light, significant eye discharge, or a persistent sensation of something in the eye. If you experience any itching, redness, or pain around the eyes, or if your vision becomes blurry or abnormal, it is important to contact a healthcare provider promptly.

In very rare instances, a severe allergic reaction may occur. Symptoms to watch for include rash, itching, swelling particularly of the face, tongue, or throat, severe dizziness, and difficulty breathing. Should these symptoms arise, seek emergency medical help immediately. If you notice any other unusual effects not listed, it's best to discuss these with your healthcare provider. Remember, while side effects can occur, many people experience no significant issues when using this medication.

Please be aware of potential interactions when using Bromfenac with other medications. Inform your doctor and pharmacist about all the medicines and supplements you are currently taking, whether they are prescribed, over-the-counter, or herbal. Some notable interactions include:

1. Not Recommended Combinations: Bromfenac should not be used with Ketorolac, as this combination is generally not advised.

2. Cautionary Combinations: While it's usually not recommended to combine Bromfenac with certain medications, it might be necessary in some situations. In such cases, your doctor might adjust the dosage or frequency of either drug. This group includes a wide range of medications such as Abciximab, Aspirin, Clopidogrel, and Warfarin, among others. These drugs can increase the risk of side effects when used together with Bromfenac.

3. Possible Side Effects: Using Bromfenac with medications like Acebutolol, Atenolol, and Losartan may heighten the risk of certain side effects. However, your healthcare provider might determine that the benefits outweigh the risks and could adjust dosages accordingly.

If your doctor has advised you to take low-dose aspirin (81-162 mg daily) to prevent heart attacks or strokes, you should continue with this regimen. Always consult with your healthcare provider for any concerns or questions regarding drug interactions and follow their guidance for safe medication use.