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The safety and warning information for Capron DM (dextromethorphan / pyrilamine) is essential for ensuring safe use of the medication. Please review the following details carefully and consult your healthcare provider with any questions or concerns.

• Serotonin Syndrome: This medication may increase the risk of serotonin syndrome, a rare but serious condition caused by excessive serotonin in the brain. Symptoms include rapid heartbeat, sweating, muscle stiffness, fever, and confusion. The risk is heightened when combined with other medications affecting serotonin levels, such as SSRIs, SNRIs, and MAOIs. Ensure your healthcare provider is aware of all medications you are taking, and do not start new medications without consulting your healthcare provider or pharmacist. Immediate medical attention is necessary if symptoms of serotonin syndrome occur.

• Drowsiness: Capron DM can cause significant drowsiness, potentially impairing your ability to concentrate or react. This effect may be intensified if you are over 65, consume alcohol, or take other sedatives such as opioids and benzodiazepines. Refrain from operating vehicles or heavy machinery until you understand how the medication affects you.

• Accidental Overdose: This product contains a cough suppressant and an antihistamine, both of which are found in other over-the-counter medications. Using multiple products containing these ingredients can lead to overdose, resulting in breathing difficulties, excessive sleepiness, dizziness, and seizures. Be cautious when using multiple medications.

• Exacerbation of Medical Conditions: Avoid using Capron DM if you have certain health conditions unless approved by your healthcare provider. The medication can worsen existing conditions and lead to serious side effects. Inform your healthcare provider of any existing or past medical conditions, especially if you have a cough linked to smoking, asthma, emphysema, or if you have heart disease, thyroid issues, diabetes, or urinary problems.

• Contraindications: Do not use Capron DM if you have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days, as this can pose serious health risks.

Adhere to these precautions to ensure safe use of Capron DM, and seek medical advice when necessary.

When taking this medication, you may experience some common side effects such as drowsiness, dizziness, blurred vision, nausea, vomiting, constipation, dry mouth, or trouble sleeping. These are generally mild, but if they persist or worsen, it is advisable to consult your healthcare provider for guidance.

There are other side effects that, while less common, can still occur. These include an upset stomach and trouble urinating. Should you experience these, especially if they become bothersome, seeking medical advice is important.

More serious side effects, although rare, require immediate medical attention. These include fast, irregular, or pounding heartbeat, mental or mood changes such as confusion or hallucinations, seizures, and shaking (tremors). Additionally, signs of serotonin syndrome—characterized by a fast heart rate, sweating, muscle stiffness, fever, and confusion—are critical and need urgent care. An overdose can manifest through seizures, heart rhythm issues, hallucinations, or loss of consciousness.

A very serious allergic reaction to the drug is rare, but if you notice symptoms like a rash, itching, swelling particularly of the face, tongue, or throat, severe dizziness, or trouble breathing, seek emergency medical assistance immediately. Always report any other unexpected side effects to your healthcare provider.

When using this medication, it is important to avoid certain MAO inhibitors, as combining them can lead to a serious and potentially fatal interaction. Do not take isocarboxazid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, or Tranylcypromine while on this medication. Additionally, most MAO inhibitors should not be used for at least two weeks prior to starting this treatment. Consult your doctor for guidance on when to begin or discontinue this medication.

Inform your healthcare provider if you are taking any other products that may cause drowsiness. These include opioid pain or cough medications like codeine or hydrocodone, alcohol, marijuana, sleep or anxiety drugs such as Alprazolam, Lorazepam, or Zolpidem, muscle relaxants like Carisoprodol or Cyclobenzaprine, and other antihistamines such as Cetirizine or diphenhydramine.

Be sure to examine the labels on all your medications, especially those for allergies or cough-and-cold, as they may contain ingredients that cause drowsiness or are similar to this medication. Consult your pharmacist to ensure safe use of these products.

This drug can interfere with certain laboratory tests, potentially leading to inaccurate results, particularly with urine drug screenings or allergy skin tests. It is important to inform lab personnel and all your healthcare providers that you are using this medication.