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Diabetic Neuropathy

Diabetic neuropathy is a chronic condition affecting the nerves in individuals with diabetes. It causes symptoms such as pain, numbness, and muscle weakness. Treatment options include medications, physical therapy, and lifestyle modifications. Preventive measures include managing blood sugar levels and proper foot care.

Best medications for Diabetic Neuropathy

Drug NameClassRouteStandard DosagePrice
CymbaltaSNRIsOral60, 20, 30 MGfrom$10.46
LyricaAnti-epilepticsOral225, 150, 200, 300, 20, 50, 75, 165, 330, 25, 82.5, 100 MGfrom$10.60
Lyrica CRAnti-epilepticsOral165, 330, 82.5 MGfrom$42.26
Drizalma SprinkleSNRIsOral40, 60, 20, 30 MGfrom$206.94
FoltanxMedical FoodsOral3-90.314-2-35, 3-35-2 MGfrom$25.73
RegranexHuman Platelet-Derived Growth FactorsExternal0.01 %from$528.18


Diabetic neuropathy is a chronic complication of diabetes that affects the nerves, most commonly those in the extremities such as the feet and legs. It is estimated that around 50% of individuals with diabetes develop neuropathy at some point during their disease progression. Diabetic neuropathy occurs as a result of high blood glucose levels damaging the small blood vessels that supply oxygen and nutrients to the nerves. This damage leads to malfunctioning and eventual degeneration of the nerves, causing a range of symptoms.


The symptoms of diabetic neuropathy can vary depending on the type and location of the nerves affected. Some common symptoms include: 1. Peripheral neuropathy: This is the most common type of diabetic neuropathy. Symptoms include numbness, tingling, and pain in the feet, legs, hands, and arms. These sensations may worsen at night. 2. Autonomic neuropathy: This type of neuropathy affects the autonomic nerves, which control involuntary functions such as digestion, blood pressure, and heart rate. Symptoms may include dizziness, difficulty swallowing, constipation, diarrhea, bladder problems, and sexual dysfunction. 3. Proximal neuropathy: This type affects the muscles of the thighs, hips, buttocks, and legs. Symptoms may include severe pain, muscle weakness, and difficulty moving. 4. Focal neuropathy: Focal neuropathy affects specific nerves, causing sudden weakness or pain in a single nerve or group of nerves. For example, it may cause weakness in the muscles of the face or intense pain in the lower back or leg.


While complete resolution of diabetic neuropathy may not always be possible, managing blood sugar levels is crucial in preventing further nerve damage and alleviating symptoms. Additionally, the following treatments may be recommended: 1. Medications: Various medications, such as antidepressants, anticonvulsants, and pain relievers, may be prescribed to manage the symptoms of diabetic neuropathy. These medications work by targeting the specific types of pain associated with neuropathy. 2. Topical treatments: Creams or patches containing capsaicin, a substance found in chili peppers, can provide temporary pain relief when applied to the affected areas. 3. Physical therapy: Physical therapy exercises and techniques can help improve muscle strength, balance, and coordination, which can alleviate some neuropathy symptoms. 4. Transcutaneous electrical nerve stimulation (TENS): TENS involves the use of a small, portable device that delivers low-level electrical currents to the affected area. This can help reduce pain and improve nerve function. 5. Lifestyle modifications: Proper foot care, regular exercise, maintaining a healthy weight, and quitting smoking can all have a positive impact on diabetic neuropathy symptoms. These lifestyle changes can help manage blood sugar levels, improve circulation, and reduce the risk of further nerve damage.


While not all cases of diabetic neuropathy can be prevented, there are steps individuals with diabetes can take to reduce their risk: 1. Monitor blood sugar levels: By regularly monitoring blood sugar levels and keeping them within the target range recommended by healthcare professionals, the risk of developing neuropathy can be reduced. 2. Proper foot care: Regularly checking the feet for cuts, blisters, or any signs of infection can prevent minor issues from developing into more severe complications. Maintaining good foot hygiene and wearing proper footwear is also essential. 3. Healthy lifestyle choices: Following a balanced diet, engaging in regular exercise, and avoiding smoking can all contribute to better diabetes management and lower the risk of developing complications. In conclusion, diabetic neuropathy is a common complication of diabetes characterized by damage to the nerves. By carefully managing blood sugar levels and following prescribed treatments, individuals with diabetes can reduce their risk of developing neuropathy or alleviate its symptoms.