Endari Coupons & Savings Card – Discount Prices from $728.98
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5GM, Endari (30 Packets)
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Walgreens
$728.98
COUPON PRICEEndari savings card
Show this card to your pharmacistWalgreens
$728.98
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019876
LH9D988ED7
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LHX
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Price history for Endari
30 Packets, 5GM
Average retail price for Endari
Average SaveHealth price for Endari
Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.
*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.
Endari dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 5GM | 30 Packets | $728.98 | $24.30 |
Endari Warnings
When considering Endari for the management of sickle cell disease, it's important to be aware of certain safety considerations:
Use in Children Under 5 Years: The safety and effectiveness of Endari have not been established in children younger than 5 years old.
Pregnancy and Breastfeeding: There is limited information on the use of Endari during pregnancy and breastfeeding. It's advisable to consult with a healthcare provider to weigh the potential benefits and risks before using Endari in these situations.
Overdose: In animal studies, very high doses of L-glutamine, the active ingredient in Endari, have been associated with serious effects. While such doses are much higher than those prescribed for humans, it's crucial to adhere strictly to the dosing instructions provided by your healthcare provider to avoid potential risks.
Always discuss any concerns or questions with your healthcare provider to ensure that Endari is appropriate and safe for your specific health needs.
Endari Side Effects
When taking this medication, some common side effects you might experience include constipation, nausea, headache, stomach pain, cough, and back pain. These effects are generally mild and often resolve on their own. If they persist or worsen, it's important to consult your healthcare provider for advice. In some cases, individuals may experience pain in the arm or leg, chest pain, or other discomforts. While these are not as common, they should be monitored, and you should reach out to your healthcare provider if they become troublesome. Allergic reactions are rare but serious and require immediate medical attention. Symptoms to watch for include rash, itching, hives, and swelling, particularly of the face, lips, tongue, or throat. If you encounter any of these signs, seek medical help right away. While serious side effects are uncommon, they include severe back pain, constipation, cough, headache, nausea, and stomach pain. These need urgent medical attention, so please seek help promptly if you experience any of these severe reactions. Always stay attentive to how your body responds to the medication, and never hesitate to discuss any concerns with your healthcare provider.
Endari Interactions
When considering the use of Endari (L-Glutamine) for sickle cell disease, it's important to be aware of potential interactions with other medications and health conditions. Currently, there are no well-documented drug interactions with Endari. However, it's essential to inform your healthcare provider about all medications, supplements, and herbal products you are taking to ensure safety.
Endari is metabolized into glutamate and ammonia, substances that may accumulate in individuals with liver impairment. Therefore, if you have liver disease, your doctor may need to monitor your condition more closely while you're on Endari.
Additionally, if you're considering gene therapy treatments like exagamglogene autotemcel for sickle cell disease, it's important to discuss the timing of Endari use with your healthcare provider. The manufacturers of exagamglogene autotemcel recommend discontinuing disease-modifying treatments, including Endari, before collecting blood stem cells for the therapy.
While no specific food interactions have been identified with Endari, it's advisable to consult your doctor regarding alcohol consumption during treatment. Excessive alcohol intake can lead to dehydration, which may trigger pain crises in individuals with sickle cell disease.
Always consult your healthcare provider before starting or stopping any medication to ensure it aligns with your overall treatment plan and health status.
What is the drug Endari used for?
Endari is used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older.
Is Endari FDA approved?
Yes, Endari is FDA approved. It was approved by the U.S. Food and Drug Administration in July 2017 for the treatment of sickle cell disease in patients aged five years and older.
What is the mechanism of action of Endari?
Endari, which is L-glutamine oral powder, works by increasing the availability of free glutamine in the blood. This helps to reduce oxidative stress in sickle cell red blood cells, thereby improving their flexibility and reducing the frequency of sickle cell crises. By enhancing the redox potential, Endari helps to maintain the integrity of red blood cells and reduce the complications associated with sickle cell disease.
What are the major indications for endari?
Endari is primarily indicated for the treatment of sickle cell disease in adult and pediatric patients aged five years and older. It is used to reduce the acute complications associated with the disease.
How much does Endari cost?
The cost of Endari can vary based on factors such as the pharmacy, location, and insurance coverage. Without insurance, the price can be quite high, often several thousand dollars for a month's supply. It is advisable for individuals to check with their specific pharmacy and insurance provider for the most accurate and up-to-date pricing information. Additionally, there may be patient assistance programs available to help reduce the cost.