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The following information outlines essential safety details and warnings concerning the use of Gynazole-1 (butoconazole). Please review these points carefully, and consult your healthcare provider if you have any questions or concerns.

• Allergic Reactions: While rare, severe allergic reactions to Gynazole-1 (butoconazole) may occur. Symptoms such as hives, rash, swelling of the lips or tongue, and difficulty breathing could indicate an allergic reaction. In case of anaphylaxis, which may include throat closure, seek emergency medical help immediately by calling 911. If any allergic symptoms arise, contact your healthcare provider without delay.

• Impact on Condoms and Diaphragms: The use of Gynazole-1 (butoconazole) can compromise the integrity of condoms and diaphragms, leading to potential breakage. This increases the risk of unintended pregnancies and transmission of sexually transmitted infections (STIs). This weakening effect may last up to 72 hours after application of the medication. It is advisable to refrain from sexual activity until the infection is fully resolved, as intercourse may exacerbate symptoms and potentially transmit the infection to a partner.

• Pregnancy Precaution: The safety of Gynazole-1 (butoconazole) in pregnant individuals has not been extensively studied, and its use during pregnancy is not recommended. Alternative treatments with a better-established safety profile are available for managing vaginal yeast infections in pregnant women. Please consult your healthcare provider for safer options.

In the case of additional concerns or adverse reactions, it is recommended to consult with a healthcare professional for further guidance.

When taking this medication, you may experience some mild side effects such as increased burning, itching, or soreness in the vaginal or urethral area. Some individuals also report mild abdominal cramps, pelvic discomfort, or stomach pain. These side effects occur in a small percentage of users, typically around 6%, and are usually not cause for concern. However, if these symptoms persist or worsen, it is advisable to consult your healthcare provider for guidance.

While serious side effects are rare, it is important to be aware of them. A severe allergic reaction is uncommon but requires immediate medical attention. Symptoms of such a reaction include rash, severe itching or swelling, particularly of the face, tongue, or throat, severe dizziness, and difficulty breathing. If you experience any of these symptoms, seek emergency medical help promptly.

This summary does not cover all possible side effects. If you notice any other unusual symptoms, it is important to contact your healthcare provider for further advice.