Methenamine Hippurate

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methenamine hippurate

Methenamine is a medication used to prevent and manage recurring urinary tract infections (UTIs) caused by specific bacteria. It is not intended for the treatment of active infections; antibiotics should be used initially to address such cases. Methenamine functions by inhibiting bacterial growth in the urine. This medication is most effective in an acidic urine environment, where it converts into formaldehyde, a substance that kills bacteria. It is important to note that methenamine is specifically for bacterial infections in the urinary tract and will not be effective for other infections, such as those in the bloodstream or viral infections like the common cold or flu. The drug is available in two forms: methenamine hippurate (Hiprex), taken twice daily, and methenamine mandelate, taken four times a day. While it generally has few side effects, some users may experience nausea, upset stomach, or painful urination. Misuse or unnecessary use of methenamine can reduce its effectiveness over time. Always consult a healthcare professional before starting any medication.
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1GM, Methenamine Hippurate (30 Tablets)

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CVS

$23.70

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$14.31

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$15.53

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$15.68

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$22.76

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Hiprex dosage forms

The average cost for 30 Tablets of Hiprex (methenamine hippurate) at 1GM is $14.31 with a free coupon. This is 27.10% off the average retail price of $52.8
DosageQuantityPrice fromPer unit
1GM30 Tablets$14.31$0.48

Hiprex Warnings

This medication comes with critical safety considerations that you should be aware of. The points below outline potential risks, necessary precautions, and specific instructions to ensure safe use. Please discuss any concerns with your healthcare provider.

  • Liver Health Concerns: Methenamine hippurate (Hiprex) may cause a temporary increase in liver enzyme levels, indicating possible liver irritation or damage. This is particularly important if you have a history of liver disease. Regular blood tests may be required to monitor liver function. This medication is not suitable for individuals with severe liver conditions.

  • Bladder Issues and Urination: Exceeding the recommended dose of methenamine hippurate (Hiprex) can lead to bladder irritation, frequent and painful urination, and the presence of protein or blood in your urine. It is crucial to adhere to the prescribed dosage. Report any of these symptoms to your healthcare provider immediately.

  • Drug Interactions: Avoid using methenamine hippurate (Hiprex) in conjunction with sulfonamide medications, such as sulfamethoxazole/trimethoprim (Septra, Bactrim), as this combination can result in the painful formation of crystals.

  • Contraindications: Do not use this medication if you have serious liver or kidney problems, severe dehydration, or if you are taking sulfonamide medications. These conditions could lead to severe health complications.

Always follow your healthcare provider’s instructions and seek their advice if you encounter any issues or have questions regarding the use of this medication.

Hiprex Side Effects

When taking methenamine, you might experience some common side effects, such as nausea, vomiting, diarrhea, abdominal cramps, and a loss of appetite. These are typically mild, but if they persist or worsen, it's important to consult with your healthcare provider. Less frequently, individuals might experience painful or difficult urination. If this occurs, it could be necessary to adjust your dosage or treatment plan.

Taking more than the recommended dose can lead to bladder irritation, painful or frequent urination, and even bloody or pink urine. If you experience any of these symptoms, it's crucial to seek medical advice immediately. Although serious side effects are rare, you should be aware of the possibility of mouth sores, unusual headaches, ringing in the ears, muscle cramps, or swelling of the arms and legs. These symptoms require prompt medical attention.

A very serious allergic reaction to methenamine is uncommon, but if you experience a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing, seek emergency medical help right away. This summary does not cover all possible side effects, so if you notice any other unusual symptoms, contact your doctor or pharmacist.

Hiprex Interactions

Some products that may interact with this drug include: sulfonamide drugs (including sulfa antibiotics such as sulfamethizole), products that decrease the amount of acid in the urine (urinary alkalinizers such as antacids, sodium bicarbonate, potassium or sodium citrate, carbonic anhydrase inhibitors such as acetazolamide). This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Hiprex FAQs
Can I buy Hiprex over the counter?

Hiprex is typically available by prescription only in many countries. It is advisable for the individual to consult with a healthcare provider to obtain a prescription and ensure it is appropriate for their condition.

Hiprex, which contains methenamine, is used to help prevent urinary tract infections (UTIs) rather than treat an active infection. It works by turning into formaldehyde in the urine, which has antibacterial properties. For an active UTI, antibiotics are typically required to eliminate the infection. It is important for individuals to consult with a healthcare provider for appropriate diagnosis and treatment of a UTI.

Methenamine can be used to help prevent urinary tract infections (UTIs), but it is not typically used to treat an active infection. It works by turning into formaldehyde in the urine, which can help suppress bacterial growth. For an active UTI, antibiotics are usually prescribed to clear the infection. Methenamine is more effective as a preventive measure in individuals who experience recurrent UTIs.

The cost of Hiprex without insurance can vary depending on the pharmacy and location. On average, the price for a supply of 100 tablets of 1 gram each can range from $70 to $100. It's advisable to check with local pharmacies for the most accurate pricing. Additionally, using a prescription discount card or service may help reduce the cost.

Hiprex, which contains methenamine, can have several side effects in the elderly. Common side effects may include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. Some elderly patients may also experience skin rashes or allergic reactions. Less commonly, it can cause bladder irritation or painful urination. It is important for elderly patients to be monitored for any unusual symptoms or side effects, and they should consult their healthcare provider if they experience any adverse effects.