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It is important to be aware of certain safety considerations when using Uribel Tabs. Below are key warnings and potential risks associated with this medication. Please discuss any concerns with your healthcare provider.

• Agitation, Drowsiness, or Confusion: Uribel Tabs may cause excitement, agitation, drowsiness, or confusion, particularly in individuals aged 65 and older. If these effects become troubling, inform your healthcare provider.

• Serious Medication Interactions: This medication contains methylene blue, which can inhibit the breakdown of serotonin. If you are taking medications that increase serotonin levels, such as fluoxetine (Prozac), there is a risk of developing serotonin syndrome—a serious condition characterized by confusion, muscle twitching, shaking, and diarrhea. Always inform your healthcare provider if you are on such psychiatric medications.

• Allergic Reactions: If you have previously experienced allergic reactions to belladonna alkaloids (e.g., atropine, scopolamine) or salicylates (e.g., aspirin), you may also be at risk of an allergic reaction to Uribel Tabs. Ensure your healthcare provider is aware of any past allergies.

• Stomach-Related Issues: Uribel Tabs can slow digestion, which may exacerbate conditions such as stomach ulcers. Notify your healthcare provider if you have a stomach ulcer before starting this medication.

• Long-term Use: The safety of prolonged use of Uribel Tabs is not well-established. It is crucial to evaluate the risks and benefits of long-term use with your healthcare provider.

Always consult your healthcare professional before starting or stopping any medication, and report any unusual symptoms immediately.

When taking this medication, you may experience some common side effects, which are usually mild and manageable. These include nausea, vomiting, dry mouth, dizziness, drowsiness, blurred vision, and constipation. Additionally, you might notice that your urine or stools appear blue-green; this is harmless and will subside once you stop the medication. To ease dry mouth, try sugarless gum or candy, drink water, or use a saliva substitute.

There are some less common but more serious side effects that require prompt attention. These include hot, dry, flushed skin, decreased sweating, eye pain, and difficulty urinating. If you notice changes in urination, such as pain or a significant change in amount, contact your healthcare provider. Serious allergic reactions, though rare, may occur. Seek immediate medical help if you experience rash, itching, swelling, severe dizziness, or trouble breathing.

In rare cases, this medication can lead to severe side effects such as easy bruising, black or tarry stools, or stomach pain. If you notice persistent nausea, vomiting that resembles coffee grounds, unusual tiredness, dark urine, or yellowing of the skin or eyes, these could indicate liver problems and require urgent medical attention. Additionally, be aware of symptoms of a hypertensive crisis, such as a severe headache, irregular heartbeat, neck stiffness, or vision changes, which need immediate medical care.

Remember, while these side effects can occur, many people use this medication without experiencing any severe reactions. Always inform your healthcare provider about any side effects you encounter to ensure safe and effective use of the medication.

This medication can interact with various other products and medications, which may affect its efficacy or increase the risk of side effects. Some of these include:

• Drugs that may interact: Apraclonidine, atomoxetine, bupropion, carbamazepine, dichlorphenamide, methotrexate, mifepristone, potassium supplements, pramlintide, tetrabenazine, certain medications for Parkinson's disease (such as entacapone, levodopa, tolcapone), certain blood pressure medications (like guanethidine, methyldopa), sulfonamide drugs (including antibiotics like sulfamethoxazole), and sympathomimetics (such as amphetamine, ephedrine). Medications that reduce acid in the urine, such as antacids and sodium bicarbonate, can also interact.

• Increased bleeding risk: This drug may heighten bleeding risk when taken with other medications that cause bleeding, such as anti-platelet drugs (like clopidogrel) and anticoagulants (such as dabigatran, enoxaparin, and warfarin).

• MAO inhibitors: Combining this medication with other MAO inhibitors can lead to serious, potentially fatal interactions. Avoid using isocarboxazid, linezolid, metaxalone, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine both during and two weeks before and after treatment. Consult with your healthcare provider for guidance on when to start or stop this medication.

• Hypertensive crisis risk: Some substances, including certain herbal products (like ephedra/ma huang), nasal decongestants (such as phenylephrine, pseudoephedrine), stimulants (amphetamines, ephedrine, epinephrine), and diet aids, may significantly raise blood pressure when used with this medication. Avoid using these together.

• Azole antifungal drugs: If you are taking azole antifungals (such as itraconazole or ketoconazole), ensure this medication is taken at least two hours after the antifungal.

• Pain relievers/fever reducers: Many over-the-counter medications contain pain relievers like aspirin or NSAIDs (such as ibuprofen, ketorolac, naproxen), which can increase side effects if taken with this medication. However, continue low-dose aspirin for heart attack or stroke prevention as prescribed by your doctor.

• Drowsiness-inducing products: Alcohol, marijuana, antihistamines (like cetirizine, diphenhydramine), sleep or anxiety drugs (such as alprazolam, diazepam, zolpidem), muscle relaxants, and opioid pain relievers (like codeine) may enhance drowsiness. Check all medication labels for ingredients that cause drowsiness and consult your pharmacist on safe use.

• Lab test interference: This medication could affect certain laboratory tests, potentially leading to false results. Ensure all healthcare providers and laboratory personnel are aware of your medication use.

For your safety, always consult with your healthcare provider or pharmacist before starting or stopping any medication.