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Hyoscyamine is a medication with specific safety considerations and warnings that are important to understand for safe use. Below are key points to consider, along with guidance on when to contact your healthcare provider:

• Dizziness and Vision Impairment: This medication may cause dizziness, drowsiness, and blurred vision. Avoid driving or engaging in activities that require full alertness until you are familiar with how hyoscyamine affects you.

• Mental and Behavioral Changes: Hyoscyamine may alter your mood, thoughts, or cognitive functions, potentially causing confusion, memory issues, or disorientation. In some cases, it can lead to agitation, hallucinations, or euphoria, and in severe cases, a coma. These effects generally subside within 12 to 48 hours after discontinuing the medication. Notify your healthcare provider immediately if you notice any changes in mood or behavior, especially if you are aged 65 or older or have mental health conditions.

• Increased Heart Rate: Inform your healthcare provider if you have existing heart conditions such as heart failure, previous heart attacks, or hypertension. Hyoscyamine can increase your heart rate, potentially exacerbating these conditions. Seek medical advice if you experience a noticeable change in heart rate or symptoms like a pounding or racing heart.

• Autonomic Function Alterations: The medication may affect involuntary bodily functions, leading to issues such as constipation, dry mouth, and reduced sweating, which could increase the risk of heat stroke. It may also affect heart rate and vision. If you develop a fever, consult your healthcare provider before continuing with hyoscyamine. Older adults are at greater risk for these effects.

• Urination Issues: Use hyoscyamine cautiously if you have prostate problems, as it can aggravate the condition and cause difficulty urinating.

• Digestive System Concerns: If you have had procedures like a colostomy, inform your provider before using hyoscyamine for diarrhea. Diarrhea could indicate a bowel blockage, and hyoscyamine may worsen the situation.

Contraindications: Hyoscyamine should not be used if you have any of the following conditions, as it may pose significant health risks. Consult your healthcare provider for guidance:

• Glaucoma
• Urinary tract obstruction
• Intestinal or stomach blockage
• Chronic constipation
• Unstable heart or bleeding disorders
• Severe ulcerative colitis with toxic megacolon
• Myasthenia gravis

If you experience any severe or concerning symptoms, or suspect an overdose, seek emergency medical assistance immediately. Always discuss any concerns or pre-existing conditions with your healthcare provider before starting hyoscyamine.

When taking this medication, you might experience some common side effects that are usually mild. These include dizziness, drowsiness, blurred vision, dry mouth, headache, trouble sleeping, constipation, flushing, dry skin, and decreased sweating. Simple remedies like sucking on sugarless candy, chewing sugarless gum, or drinking water can help alleviate dry mouth. It's also common to notice an empty medication shell in your stool, which is harmless.

In some cases, you may encounter more bothersome effects such as trouble urinating, dry eyes, or head intolerance. If you experience these or if the common side effects persist or worsen, it is advisable to consult your healthcare provider.

On rarer occasions, serious side effects may occur, necessitating immediate medical attention. Watch for symptoms such as severe mood changes, fast or irregular heartbeat, loss of coordination, trouble speaking, or vomiting. Other severe reactions include eye pain, vision changes, or signs of an allergic reaction like rash, swelling, or trouble breathing. Should any of these occur, seek urgent medical care.

This overview does not cover all possible side effects. If you notice any other unusual effects, contact your healthcare provider for advice.

When taking this medication, it is important to be aware of potential interactions with other drugs. Some antifungal medications like Ketoconazole and Itraconazole, as well as bisphosphonates (such as Alendronate and Risedronate), corticosteroids like Prednisone, and specific forms of Digoxin could interact with this drug. Additionally, potassium supplements and pramlintide should be used cautiously. Notify your healthcare provider if you are using any products that induce drowsiness, such as opioid pain relievers (e.g., codeine, hydrocodone), alcohol, cannabis, sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants like Carisoprodol and Cyclobenzaprine, or antihistamines such as Cetirizine and diphenhydramine.

This medication can also interfere with certain laboratory tests, potentially leading to inaccurate results. Ensure that all your healthcare providers and lab personnel are informed that you are using this medication. Always inform your doctor and pharmacist about any other medications or supplements you are taking, including over-the-counter drugs and herbal products, as this list does not cover all possible interactions.