Lokelma

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Lokelma, with the generic name sodium zirconium cyclosilicate, is prescribed for adults to manage high potassium levels, a condition known as hyperkalemia. This medication functions by binding to potassium in the digestive tract, preventing its absorption into the bloodstream. As a result, potassium is expelled from the body through bowel movements, helping to reduce blood potassium levels. Lokelma is not intended for immediate relief and should not be used for life-threatening potassium elevations. It is available as a powdered form that is mixed with water. Typically, dosing is personalized according to potassium levels, with a common regimen involving daily oral intake after the initial two days. A frequent side effect of Lokelma is fluid retention, leading to swelling. Always consult healthcare professionals for advice tailored to your specific health needs before starting any new medication.
Our Lokelma coupons are free to use. You can print the coupon, email it to yourself, or receive the Lokelma coupon via text message. To get your free discount, show the pharmacist your Lokelma savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Lokelma prices will update based on your prescription needs. Above our Lokelma coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Lokelma savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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10GM, Lokelma (30 Packets)

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CVS

$860.93

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Albertsons

$805.68

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Rite Aid

$849.10

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$875.28

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$886.27

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Lokelma savings card

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$860.93

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Lokelma dosage forms

The average cost for 30 Packets of Lokelma at 5GM is $823.35 with a free coupon. This is 26.94% off the average retail price of $3056.43
DosageQuantityPrice fromPer unit
5GM30 Packets$823.35$27.45
10GM30 Packets$823.19$27.44

Lokelma Warnings

This safety information highlights important considerations for the use of Lokelma. Please read the following points carefully and consult your healthcare provider if you have any questions or concerns.

  • Gastrointestinal Concerns: If you have pre-existing stomach issues, such as a blockage in your gut or severe constipation, discuss with your healthcare provider before using Lokelma. The medication may exacerbate these conditions, potentially leading to severe constipation, bowel obstruction, or delayed bowel movements post-surgery.

  • Edema (Swelling): Lokelma contains sodium, which can cause swelling in the arms, legs, or other areas of the body. This is particularly concerning for individuals with heart failure or kidney problems who need to monitor their sodium intake. If you experience swelling, shortness of breath, need multiple pillows to sleep comfortably, or notice sudden weight gain, contact your healthcare provider. High-risk factors include heart failure, renal issues, excessive sodium consumption, and taking 15 grams of Lokelma daily.

  • Hypokalemia Risk: Individuals undergoing hemodialysis may experience a decrease in potassium levels (hypokalemia) when taking Lokelma. This risk is heightened during periods of illness with symptoms such as vomiting or diarrhea, reduced appetite, or when using potassium-lowering medications like loop diuretics. Should you become ill or commence new medications, inform your healthcare provider as your dosage may need to be adjusted, and laboratory tests may be required to monitor your potassium levels.

There are no known contraindications for Lokelma at this time.

Lokelma Side Effects

When taking this medication, some individuals may experience swelling in the hands, legs, or feet. These are common side effects and usually mild. If they persist or worsen, it's advisable to consult your healthcare provider for guidance. Additionally, some people might encounter low potassium levels or constipation, which should also be discussed with a healthcare professional if they occur.

In rare cases, more serious side effects can arise, necessitating immediate medical attention. These include severe allergic reactions, which may present as a rash, itching, hives, or swelling of the face, lips, tongue, or throat, as well as symptoms of low potassium such as muscle pain or cramps, unusual weakness or fatigue, and a fast or irregular heartbeat. Should these symptoms appear, it is crucial to seek urgent medical care.

Lokelma FAQs
What is Lokelma used for?

Lokelma is used for the treatment of hyperkalemia, which is a condition characterized by elevated levels of potassium in the blood.

Lokelma and Kayexalate are both medications used to treat hyperkalemia, which is a condition characterized by elevated levels of potassium in the blood. However, they differ in their composition and mechanism of action. Lokelma (sodium zirconium cyclosilicate) works by exchanging sodium ions for potassium ions in the gastrointestinal tract, thereby reducing potassium levels. Kayexalate (sodium polystyrene sulfonate) also exchanges sodium for potassium but has a different chemical structure. Both medications aim to lower potassium levels, but they may have different side effect profiles and dosing regimens. It is important for patients to follow their healthcare provider's recommendations when using these medications.

Lokelma (sodium zirconium cyclosilicate) is generally considered safe for the kidneys. It is used to treat hyperkalemia, a condition characterized by high potassium levels in the blood, which can be harmful to the kidneys if left untreated. Lokelma works by binding potassium in the gastrointestinal tract, thereby reducing its levels in the blood. However, as with any medication, it is important for patients to use it under the guidance of a healthcare provider, who will monitor kidney function and overall health to ensure its safe use.

The fastest way to decrease potassium levels in the body is through the use of intravenous calcium gluconate, which stabilizes the heart muscle, followed by insulin with glucose. Insulin helps to shift potassium from the blood into the cells, effectively lowering blood potassium levels quickly. Additionally, beta-agonists like albuterol can also be used to help shift potassium into cells. However, these treatments are typically used in acute settings and should be administered under medical supervision.

Lokelma, which is a brand name for sodium zirconium cyclosilicate, is used to treat hyperkalemia (high potassium levels in the blood). An equivalent medication is patiromer, marketed under the brand name Veltassa. Both medications are used to lower potassium levels, but they have different mechanisms of action and dosing schedules. It is important for patients to consult with their healthcare provider to determine the most appropriate treatment for their condition.