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This medication carries certain safety warnings that are crucial for your well-being. It is important to be aware of these risks and take appropriate precautions. Please review the information below and consult your healthcare provider if you have any concerns:

• Liver Damage: Although rare, there have been instances of liver damage associated with the use of chlorzoxazone (Lorzone). Watch for symptoms such as fever, rash, loss of appetite, stomach pain, dark urine, and yellowing of the skin or eyes. If you experience any of these, discontinue use immediately and contact your healthcare provider.

• Drowsiness, Dizziness, and Lightheadedness: Chlorzoxazone (Lorzone) may cause drowsiness, dizziness, or lightheadedness. These effects can be intensified by alcohol or other sedating drugs like opioids or antihistamines. Avoid alcohol consumption while taking this medication. Ensure you understand how chlorzoxazone affects you before engaging in activities that require alertness, such as driving.

There are no specific contraindications listed for this medication. Always consult your healthcare provider for personalized advice.

When taking this medication, some individuals may experience common side effects such as drowsiness, dizziness, lightheadedness, tiredness, or an upset stomach. These effects are generally mild and temporary, but if they persist or worsen, it's advisable to consult a healthcare provider for guidance. Additionally, it is not unusual for this medication to cause harmless discoloration of the urine, turning it orange or reddish-purple, which should resolve once the medication is discontinued.

There are also less common side effects that can occur, such as skin reactions like rashes. While these are not as frequent, it's important to be aware of them and seek medical advice if they arise, especially if they are bothersome.

In rare cases, this medication can lead to serious side effects that require immediate medical attention. These include signs of severe liver damage, such as dark urine, yellowing of the skin or eyes, and upper right stomach pain. Also, watch for symptoms of stomach bleeding, such as black or bloody stools or vomit that resembles coffee grounds. Furthermore, signs of an overdose, including extreme drowsiness, dizziness, or muscle weakness, should prompt urgent medical care.

Although a very serious allergic reaction is rare, symptoms like a rash, severe dizziness, trouble breathing, or swelling of the face, tongue, or throat necessitate immediate medical assistance. Always stay informed about the potential side effects and consult a healthcare professional if you encounter any issues not listed here.

If you are using chlorzoxazone (Lorzone), it's important to inform your doctor or pharmacist about any other medications or products you are taking. This includes those that may cause drowsiness, such as opioid pain or cough medications (like codeine or hydrocodone), alcohol, marijuana, sleep or anxiety medications (such as alprazolam, lorazepam, or zolpidem), other muscle relaxants (like carisoprodol or cyclobenzaprine), and antihistamines (such as cetirizine or diphenhydramine). These can all interact with chlorzoxazone, potentially increasing drowsiness.

Additionally, chlorzoxazone may interact with a wide range of medications, which can lead to enhanced side effects or necessitate changes in dosages. Some of these medications include various opioids, benzodiazepines, barbiturates, and other central nervous system depressants. Your healthcare provider may decide to prescribe these together if the benefits outweigh the risks, adjusting dosages as necessary. Be sure to check all your medication labels for ingredients that might induce drowsiness and consult your pharmacist for safe usage.