Mavyret

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Mavyret is a medication comprising glecaprevir and pibrentasvir, prescribed for treating chronic hepatitis C, a persistent viral infection affecting the liver. This combination therapy is highly effective against various hepatitis C genotypes, including 1, 2, 3, 4, 5, and 6, in patients aged 3 years and older. It is also used for individuals previously treated with an NS5A or HCV protease inhibitor. The drug works by combining two antivirals that inhibit the virus's ability to replicate. Glecaprevir (a protease inhibitor) and pibrentasvir (an NS5A inhibitor) target different viral proteins, curbing the virus's proliferation and aiding the immune system in combating the infection, which can help the liver heal. Treatment duration with Mavyret is typically 8 weeks for patients new to hepatitis C therapy. However, those with prior treatments may require a longer course. Common side effects include headaches, tiredness, and nausea. While Mavyret reduces the virus in the body, it’s unclear if it prevents transmission. Therefore, it is important not to share needles and to practice safer sex. Always consult a healthcare professional before starting any medication.
Our Mavyret coupons are free to use. You can print the coupon, email it to yourself, or receive the Mavyret coupon via text message. To get your free discount, show the pharmacist your Mavyret savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Mavyret prices will update based on your prescription needs. Above our Mavyret coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Mavyret savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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100-40MG, Mavyret (30 Tablets)

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Walgreens

$4885.43

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Walgreens

$4885.43

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Mavyret dosage forms

The average cost for 30 Tablets of Mavyret at 100-40MG is $4580.45 with a free coupon. This is 27.42% off the average retail price of $16702.66
DosageQuantityPrice fromPer unit
100-40MG30 Tablets$4580.45$152.68

Mavyret Warnings

This medication is used to treat hepatitis C, but it is important to be aware of the potential risks and necessary precautions associated with its use. Please review the following safety information carefully and consult your healthcare provider with any concerns:

  • Liver Health Risks: This medication can rarely cause serious liver problems and may exacerbate existing liver conditions, including hepatitis B. If you have a history of hepatitis B or other liver issues, inform your healthcare provider before starting treatment. Symptoms of liver disease, such as persistent nausea, vomiting, lack of appetite, abdominal pain, dark urine, or yellowing of the eyes and skin, should be reported to your doctor immediately.

  • Hepatitis B Reactivation: Treatment for hepatitis C can lead to the reactivation of hepatitis B, particularly in those not currently receiving hepatitis B medications. This can result in mild to severe liver complications. Your healthcare provider may check for hepatitis B before initiating treatment and will need to know if you have ever had hepatitis B or received treatment for it.

  • Interactions with Other Medications: Certain medications can reduce the effectiveness of this treatment by lowering its concentration in your body. Such medications include rifampin, carbamazepine, efavirenz-containing drugs, and herbal supplements like St. John's wort. Inform your healthcare provider and pharmacist about all medications and supplements you are taking to avoid potential interactions.

  • Contraindications: This medication should not be used if you have moderate-to-severe liver problems or are taking atazanavir or rifampin simultaneously, as these combinations may pose serious health risks.

  • Emergency Measures for Overdose: In the event of an overdose, seek immediate medical attention.

By adhering to these precautions and promptly addressing any symptoms or interactions, you can help ensure the safe and effective use of this medication.

Mavyret Side Effects

When taking this medication, you might experience some common side effects such as tiredness, headache, or nausea. These are generally mild, but if they persist or worsen, it's important to consult your healthcare provider. Other side effects may include diarrhea, rash, or stomach pain. While these aren't as common, they should still be monitored if they occur.

It's crucial to be aware of serious side effects, although they are rare. A very serious allergic reaction may present symptoms like a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. If you notice any of these symptoms, seek immediate medical attention.

One critical but rare side effect is liver failure due to hepatitis B virus reactivation. This can be identified by symptoms such as nausea, stomach pain, or yellowing of the skin or eyes. Immediate medical care is essential if you experience any of these symptoms. Remember, your healthcare provider can offer guidance and support if you notice any other effects not mentioned here.

Mavyret Interactions

This medication may slow down the removal of other drugs from your system, potentially altering their effectiveness. This includes specific "statin" cholesterol medications like atorvastatin, lovastatin, and simvastatin. Additionally, certain drugs can influence how this medication is processed in your body, which might change its effectiveness. These include cyclosporine, efavirenz, HIV protease inhibitors like atazanavir and darunavir, rifampin, seizure medications such as carbamazepine, phenobarbital, phenytoin, and St. John's wort.
Mavyret FAQs
Does Mavyret really cure hep C?

Yes, Mavyret is an antiviral medication that is used to treat hepatitis C. It has been shown to be highly effective in curing the infection in many patients, with cure rates exceeding 90% in clinical trials. However, the effectiveness can vary depending on the specific genotype of the hepatitis C virus and the patient's individual health factors. It is important for patients to follow their healthcare provider's instructions and complete the full course of treatment for the best chance of achieving a cure.

The cost of Mavyret can vary depending on factors such as insurance coverage, pharmacy pricing, and location. Without insurance, the list price for a 28-day supply can be several thousand dollars. Patients are encouraged to check with their insurance provider or pharmacy for specific pricing and potential financial assistance programs.

Mavyret is used for the treatment of chronic hepatitis C virus (HCV) infection in adults and children aged 3 years and older. It is effective against all major genotypes of the virus.

Yes, hepatitis C can be effectively cured in most cases with the use of direct-acting antiviral medications. These treatments have a high success rate, often exceeding 95%, in achieving a sustained virologic response, which is considered a cure. However, the success of treatment can depend on various factors, including the specific genotype of the virus, the presence of liver damage, and adherence to the treatment regimen. It is important for individuals to consult with their healthcare provider to determine the most appropriate treatment plan.

The most common side effects of Mavyret include headache, fatigue, nausea, and diarrhea. Some individuals may also experience elevated liver enzymes. It is important for patients to discuss any side effects with their healthcare provider.

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