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Morphine is associated with a high risk of abuse and addiction, potentially leading to overdose and death. It can also cause serious, sometimes fatal, respiratory issues. To minimize these risks, it's important to use the smallest effective dose for the shortest duration as advised by your healthcare provider.

• Opioid Overdose Management: Discuss with your doctor or pharmacist whether you should have naloxone on hand to manage opioid overdoses. Educate your family or household members about recognizing opioid overdose symptoms and how to respond effectively.

• Increased Risk Periods: The risk of severe respiratory problems is heightened when starting the medication, after increasing the dose, or if the incorrect dose or strength is taken. Combining morphine with alcohol or other drugs that cause drowsiness or respiratory issues can lead to serious, potentially fatal side effects.

• Symptoms Requiring Immediate Attention: Seek immediate medical assistance if you experience severe side effects such as slow or shallow breathing, unusual lightheadedness, excessive drowsiness or dizziness, or difficulty waking up.

• Administration Instructions: Do not break, crush, chew, or dissolve this medication. Altering the form of extended-release morphine can lead to a fatal overdose.

• Secure Storage: Keep this medicine securely stored to prevent theft, misuse, or abuse. In the event of accidental ingestion, seek medical help immediately.

• Considerations for Women: Women of childbearing age should consult their healthcare providers about the medication's risks and benefits. Inform your doctor if you are pregnant or planning to become pregnant. Use during pregnancy should only occur when absolutely necessary, as it may slightly increase the risk of birth defects if taken during the first two months. Prolonged or high-dose use near delivery may harm the unborn baby. To reduce risk, adhere to the smallest effective dose for the shortest time. Newborns exposed to this drug for extended periods may experience severe withdrawal symptoms. Immediately inform a doctor if your newborn shows signs such as persistent crying, slow or shallow breathing, irritability, tremors, vomiting, diarrhea, poor feeding, or difficulty gaining weight.

You might experience nausea, vomiting, constipation, sweating, lightheadedness, dizziness, or drowsiness when taking this medication. These side effects are usually mild and may lessen as your body adjusts. If they persist or worsen, consult your healthcare provider. Constipation can be managed by consuming dietary fiber, staying hydrated, and exercising regularly. A suitable laxative might also be recommended by your pharmacist.

To minimize dizziness and lightheadedness, rise slowly from sitting or lying down. You may notice an empty tablet shell in your stool, which is harmless as the medication has been absorbed already. Remember, the benefits of this medication often outweigh the risks, and many users do not encounter serious side effects.

However, be vigilant for serious side effects such as interrupted breathing during sleep, mental or mood changes like agitation or confusion, severe stomach pain, difficulty urinating, or signs of adrenal insufficiency such as unusual tiredness or weight loss. Seek immediate medical attention if you experience fainting, seizures, very slow or shallow breathing, or severe drowsiness. Though rare, severe allergic reactions can occur, identified by symptoms like rash, swelling, severe dizziness, or breathing difficulties. If you detect any unlisted effects, contact your healthcare provider for advice.