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Morphine is associated with the risk of misuse and addiction, potentially resulting in overdose and death. It also poses a risk of severe, possibly life-threatening respiratory issues. To minimize these risks, it is crucial that your healthcare provider prescribes the lowest effective dose for the shortest duration.

• Consider discussing with your doctor or pharmacist the option of having naloxone available as a precaution for opioid overdose. Educate your family or household members on recognizing and responding to an opioid overdose.
• The likelihood of serious breathing problems increases when beginning treatment, following a dose increase, or if the incorrect dose or strength is taken.
• Combining morphine with alcohol or other substances that cause drowsiness or respiratory issues can lead to serious side effects, including death. Ensure you understand how to properly take morphine and which substances to avoid.
• Seek immediate medical attention if you experience symptoms such as slow or shallow breathing, unusual lightheadedness, severe drowsiness or dizziness, or difficulty waking up.
• Do not break, crush, chew, or dissolve extended-release morphine tablets, as this can result in a potentially fatal overdose.
• Store this medication securely to prevent theft, misuse, or abuse. If accidental ingestion occurs, seek medical help immediately.
• Women of childbearing age should discuss potential risks and benefits with their doctor before using this medication. Inform your doctor if you are pregnant or planning to become pregnant. Morphine should only be used during pregnancy when absolutely necessary, as it may slightly increase the risk of birth defects if taken during the first two months. Prolonged use or high doses near delivery may harm the unborn child. Babies born to mothers who have used morphine long-term may experience severe withdrawal symptoms. Notify a doctor if your newborn exhibits persistent crying, slow or shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight.

When taking this medication, you might experience mild side effects such as nausea, vomiting, constipation, sweating, lightheadedness, dizziness, or drowsiness. These symptoms often improve as your body adjusts. If they persist or worsen, consult your healthcare provider. To help manage constipation, increase your intake of dietary fiber, stay hydrated, and maintain regular physical activity. A suitable laxative may also be recommended by your pharmacist. To minimize dizziness and lightheadedness, rise slowly from sitting or lying positions.

Occasionally, you might notice an empty tablet shell in your stool, which is harmless as your body has already absorbed the medication. Serious side effects are uncommon but require immediate medical attention. These include interrupted breathing during sleep, severe mood changes, intense stomach pain, difficulty urinating, and signs of adrenal gland issues like unusual tiredness or weight loss. Very serious side effects, such as fainting, seizures, slow/shallow breathing, or trouble waking up, demand urgent medical care.

Although rare, allergic reactions can occur. Seek emergency help if you experience a rash, swelling (especially of the face, tongue, or throat), severe dizziness, or breathing difficulties. If you notice any other unusual effects, contact your healthcare provider promptly.