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This medication comes with important safety and warning information that you should be aware of before use. Please read the following details and consult your healthcare provider if you have any concerns:

• Smoking and Heart Problems: Smoking while using this medication increases the risk of serious heart-related issues, including blood clots, heart attacks, and strokes. This risk is particularly high for individuals over 35 years of age who smoke. If you smoke, discuss safer birth control alternatives with your gynecologist.

• Blood Clots: The medication contains ethinyl estradiol, which can increase the risk of serious blood clots. This risk is heightened for individuals over 35 who smoke, have had recent surgery, have high blood pressure or cholesterol, are obese, have diabetes, or use higher doses of estrogen. Seek immediate medical help if you notice symptoms of a blood clot.

• High Potassium Levels: The medication includes drospirenone, which might raise potassium levels, especially when taken with certain other drugs or if you have kidney, liver, or adrenal issues. Your doctor may monitor your potassium levels accordingly. Report symptoms like nausea or irregular heartbeat to your healthcare team.

• Cancer Risks: There might be an increased risk for breast and cervical cancer associated with long-term use. Individuals with a history of these cancers should discuss risks with their healthcare provider.

• Liver Issues: Avoid using this medication if you have liver problems, as it can increase the risk of benign liver tumors. Watch for symptoms like jaundice or dark urine and consult your doctor if these occur.

• Gallbladder Disease: The medication may slightly increase the risk of gallbladder problems. Discuss with your gynecologist if you have a history of gallbladder disease.

• Blood Pressure Concerns: The medication can raise blood pressure, particularly in older individuals or those with a history of hypertension. Regular monitoring may be necessary.

• High Blood Sugar and Triglycerides: Use caution if you have prediabetes, diabetes, or high triglyceride levels, as the medication can worsen these conditions. Your doctor might need to monitor your blood sugar and triglyceride levels closely.

• Headaches: Inform your gynecologist if you experience new or worsening headaches or migraines. Severe headaches may necessitate stopping the medication.

• Irregular Bleeding: Irregular bleeding or spotting may occur, especially in the first three months. If it persists or becomes heavy, consult your gynecologist.

• Depression: If you have a history of depression, you should be monitored for mood changes while using this medication. Severe changes may require discontinuation.

• Worsening of Other Conditions: Individuals with hereditary angioedema or chloasma should consult their prescriber as the medication might exacerbate these conditions.

Contraindications: This medication should not be used if you have:

• Kidney or adrenal gland issues
• High risk or history of blood clots, stroke, or heart attack
• Coronary artery disease or certain heart rhythm problems
• Uncontrolled high blood pressure
• Diabetes with complications
• Migraines with aura or any migraines if over 35
• BMI of 30 kg/m² or higher
• Liver disease
• Unexplained vaginal bleeding
• Current or past breast cancer
• Use of certain hepatitis C medications

Always discuss your medical history and current medications with your healthcare provider before starting this medication to ensure it is safe for you.

When taking this medication, you might experience some common side effects, which are usually mild and resolve on their own. These include nausea, vomiting, headaches, and breast tenderness. Some people also notice bloating, tiredness, or changes in weight. You might experience irregular menstrual bleeding or spotting, especially during the first few months of use. If these effects persist or worsen, it's important to consult your healthcare provider.

In some cases, this medication can raise blood pressure, so regular monitoring is advised. If you have unusual changes in vaginal bleeding, such as continuous spotting or sudden heavy bleeding, or if you miss periods, seek medical advice promptly. Rarely, this medication may cause serious conditions like blood clots, leading to heart attacks or strokes. Signs of such issues include shortness of breath, chest pain, severe headaches, and dizziness. Immediate medical attention is crucial if these symptoms occur.

Serious concerns, though uncommon, might involve mood changes, irritability, or a decrease in sex drive. If you notice lumps in the breast, severe abdominal pain, dark urine, yellowing of eyes or skin, or any signs of a serious allergic reaction such as rash or difficulty breathing, seek urgent medical care. Although very serious allergic reactions are rare, they necessitate immediate assistance. Always report any side effects to your healthcare provider to ensure your safety.

When using Yaz, it's crucial to be aware of potential drug interactions. Inform your doctor and pharmacist about all medications and supplements you're taking, whether they're prescribed, over-the-counter, vitamins, or herbal products.

Interactions that should be avoided:

• Certain medications like Boceprevir, Dasabuvir, Ombitasvir, Paritaprevir, Ritonavir, and Tranexamic Acid should not be used with Yaz. Your doctor might choose an alternative treatment or adjust your current medications.

Interactions that require caution:

• Some drugs should generally be avoided with Yaz but may be necessary in some cases. These include Amifampridine, Amoxicillin, Ampicillin, and many others. If these are prescribed alongside Yaz, your doctor may adjust dosages or usage frequency.

Potential for increased side effects:

• Combining Yaz with certain medications might raise the risk of side effects. These include Amitriptyline, Atazanavir, Clomipramine, and others. If both are necessary, your doctor will monitor your treatment closely and modify it if needed.

Yaz can increase potassium levels in your blood, so inform your doctor if you're using other products that have the same effect, like Aliskiren, ACE inhibitors, or NSAIDs. Additionally, some medications can lower the effectiveness of hormonal birth control, potentially leading to pregnancy. Examples include griseofulvin, Modafinil, and certain HIV drugs such as nelfinavir and Nevirapine. Discuss with your doctor whether you should use a backup birth control method and report any unusual bleeding, which may indicate decreased efficacy of your birth control.

Finally, Yaz may affect certain lab tests, potentially causing inaccurate results. Ensure that all healthcare professionals involved in your care are aware that you are taking Yaz.