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When taking this medication, some common side effects may arise, such as nausea, vomiting, headache, bloating, breast tenderness, swelling of the ankles or feet, fluid retention, and changes in weight. These symptoms are generally mild and often improve as your body adjusts. Spotting or irregular periods may also occur, especially in the initial months. If these symptoms persist or worsen, consult your healthcare provider.

It's important to monitor your blood pressure regularly, as this medication may cause an increase. If you notice a significant rise, inform your healthcare provider. Serious side effects are uncommon but require immediate attention. These include unusual changes in vaginal bleeding, symptoms of high potassium levels like muscle weakness or irregular heartbeat, and severe headaches.

Rarely, this medication can lead to life-threatening blood clots, potentially causing heart attacks, strokes, or clots in the lungs or legs. Seek urgent medical help if you experience shortness of breath, chest pain, sudden dizziness, or severe headaches. Be alert for signs of very serious side effects such as breast lumps, severe abdominal pain, dark urine, yellowing of the skin or eyes, or mood changes like depression.

An allergic reaction to this drug is rare, but if you notice symptoms like rash, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention. This summary does not include all possible side effects. If you experience any unusual symptoms, contact your healthcare provider for advice.

Certain medications can interact with this drug. These include aromatase inhibitors (like Anastrozole or Exemestane), Atazanavir combined with cobicistat, fezolinetant, ospemifene, Tamoxifen, Tizanidine, Tranexamic Acid, and some combination treatments for chronic hepatitis C, such as ombitasvir, paritaprevir, Ritonavir, with or without dasabuvir.

Drospirenone, a component of this medication, may increase potassium levels in the blood. If you are using other medications that also elevate potassium, such as Aliskiren, ACE inhibitors (including Enalapril or Lisinopril), angiotensin receptor blockers (like Losartan or Valsartan), heparin, NSAIDs (such as Ibuprofen or Naproxen), or potassium-sparing diuretics (such as Eplerenone, Spironolactone, or Triamterene), inform your doctor.

Some medications can reduce the effectiveness of hormonal birth control by lowering hormone levels, increasing the risk of pregnancy. These include griseofulvin, Modafinil, rifamycins (like Rifampin), ritonavir, St. John's wort, certain seizure medications (including barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, Topiramate), and some HIV medications (like nelfinavir or Nevirapine). Consult your doctor or pharmacist for further guidance.

Notify your doctor about any new medication you begin and discuss the need for additional birth control methods. Report any new spotting or breakthrough bleeding, as these could indicate reduced effectiveness of your birth control.

This drug may affect certain laboratory tests, potentially leading to incorrect results. Ensure that all healthcare providers and lab technicians are aware that you are taking this medication.