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Antidepressant medications are prescribed to treat various conditions, such as depression and other mental health disorders, and can offer significant benefits, including reducing the risk of suicidal thoughts or actions. Nevertheless, research indicates that a small number of individuals, particularly those under 25, might experience heightened depression, changes in mood, or suicidal thoughts when taking these medications. It is crucial to discuss the potential risks and advantages of using antidepressants with a healthcare provider, especially for individuals under 25, even if the medication is for a non-mental health condition.

• Immediately inform your doctor if you observe any signs of worsening depression or other psychiatric conditions.
• Look out for unusual behavioral changes, which may include suicidal thoughts or attempts.
• Be vigilant for mental or mood alterations, such as increased anxiety, panic attacks, difficulty sleeping, irritability, hostility, impulsive behavior, severe restlessness, or rapid speech.
• Pay extra attention to these symptoms, particularly when starting a new antidepressant or adjusting the dosage.

When taking this medication, you might experience mild side effects such as nausea, drowsiness, dizziness, trouble sleeping, loss of appetite, weakness, dry mouth, sweating, blurred vision, and yawning. These effects are generally not serious, but if they persist or worsen, it is advisable to consult a healthcare professional.

More serious side effects that require immediate attention include shaking, restlessness, an inability to stay still, decreased interest in sex, changes in sexual ability, numbness or tingling, easy bleeding or bruising, fast or irregular heartbeat, muscle weakness or spasms, and seizures. Seek medical advice promptly if any of these occur.

In rare cases, very serious risks include black stools, vomit resembling coffee grounds, eye pain, swelling or redness, widened pupils, and vision changes. Contact medical services immediately if these symptoms arise. Additionally, serotonin syndrome, a severe condition, might occur especially if combined with other serotonin-increasing drugs. Symptoms include a fast heartbeat, hallucinations, loss of coordination, severe dizziness, nausea, vomiting, diarrhea, muscle twitching, unexplained fever, and unusual agitation or restlessness.

Men may rarely experience a painful or prolonged erection lasting four or more hours, requiring urgent medical attention to prevent permanent damage. Although rare, severe allergic reactions can happen, indicated by rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, and trouble breathing. Immediate medical help is crucial if these symptoms develop. If you notice any other effects, it is important to speak with a healthcare provider.

Some medications and products can interact with this drug. These include Thioridazine and medications that can cause bleeding or bruising, like antiplatelet drugs (such as Clopidogrel), NSAIDs (such as Ibuprofen and Naproxen), and blood thinners (such as Dabigatran and Warfarin). Aspirin can also raise the risk of bleeding when taken with this drug. However, if your doctor has advised you to take low-dose aspirin (81-162 milligrams daily) for heart attack or stroke prevention, continue taking it unless instructed otherwise. Consult your doctor or pharmacist for more information.

This drug may slow down the elimination of certain medications from your body, affecting their effectiveness. Drugs that may be affected include Atomoxetine, phenothiazines, Pimozide, Risperidone, Tamoxifen, Tetrabenazine, antiarrhythmics (such as Propafenone and Flecainide), and TCA antidepressants (such as Desipramine and Amitriptyline).

Taking MAO inhibitors with this medication can lead to a severe, potentially fatal interaction. Avoid MAO inhibitors (such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, and Tranylcypromine) during and for two weeks before and after treatment. Consult your doctor about when to begin or discontinue this medication.

The risk of serotonin syndrome or toxicity increases if you also use drugs that elevate serotonin levels. These include street drugs like MDMA/"ecstasy," St. John’s wort, certain antidepressants (other SSRIs like Citalopram/Fluoxetine and SNRIs like Duloxetine/Venlafaxine), and Tryptophan. The risk is heightened when starting or increasing the dosage of these medications.

Inform your doctor or pharmacist if you take other products that cause drowsiness, such as alcohol, marijuana (cannabis), antihistamines (like Cetirizine and diphenhydramine), sleep or anxiety medications (such as Alprazolam, Diazepam, Zolpidem), muscle relaxants, and opioid pain relievers (like codeine).

Check the labels on all your medications, including allergy or cold remedies, as they may contain ingredients causing drowsiness. Ask your pharmacist how to use these products safely.

This medication might interfere with certain medical or lab tests, like brain scans for Parkinson's disease, potentially leading to false results. Ensure all medical personnel and your doctors are aware you are using this drug.