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The following safety information outlines essential warnings associated with the use of Proctofoam HC (hydrocortisone / pramoxine). It is crucial to understand these risks and discuss any concerns with your healthcare provider.

• Fire Hazard: Due to the propellant in Proctofoam HC, it is highly flammable. Handle with care during and after use. Avoid storing the canister in high temperatures above 120°F and do not puncture or expose it to open flames. Refrain from smoking or being near fire during or immediately after application.

• Hormone-Related Side Effects: Prolonged use of topical steroids such as Proctofoam HC, particularly over large skin areas, may lead to adrenal suppression, a condition where your body stops producing natural steroid hormones. Discontinuing use suddenly may result in withdrawal symptoms like swelling, rash, and burning sensations. Be cautious of extended usage, excessive application, and covering the treated area with a bandage, especially in young children.

• Skin Issues: Extended use of Proctofoam HC can increase the likelihood of skin thinning or bruising. To minimize severe skin reactions, your healthcare provider will prescribe the lowest effective dose for the shortest duration. Report any new or worsening skin problems to your healthcare provider immediately.

• Infection Risk: Long-term use of Proctofoam HC can elevate the risk of bacterial or fungal infections. It should not be used if you have an existing skin infection, as it may exacerbate the condition. Alert your healthcare provider if you experience redness, swelling, pain, pus, or if your symptoms do not improve within 2 to 3 weeks, as these could indicate a new infection.

Please ensure you adhere to these guidelines to use Proctofoam HC safely and effectively.

When using this medication, some individuals may experience mild side effects such as burning, itching, skin irritation, or dry skin. These are generally not serious but if they persist or worsen, it is advisable to consult your healthcare provider for guidance.

In some cases, other side effects may occur, including acne-like bumps, skin discoloration, rash, thinning skin, stretch marks, skin wrinkling, and hair growth. While these effects are less common, it's important to monitor them and seek medical advice if they become severe.

There are also rare but serious side effects that require immediate medical attention. These include allergic reactions characterized by skin rash, itching, hives, or swelling of the face, lips, tongue, or throat. Additionally, signs of Cushing syndrome such as increased fat around the midsection, pink or purple stretch marks, and fragile skin, as well as symptoms of high blood sugar like increased thirst or blurred vision, should be addressed urgently. Low adrenal gland function manifesting as nausea, vomiting, loss of appetite, and unusual weakness or dizziness is also critical and warrants prompt medical care.

Always be attentive to your body's reactions and do not hesitate to seek help if you experience any unusual or severe symptoms.