
Rifabutin Coupons & Savings Card – Discount Prices from $195.81
Generic for: Mycobutin
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150MG, Rifabutin (30 Capsules)
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$195.81
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$285.60
COUPON PRICERifabutin savings card
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CVS
$195.81
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Rifabutin dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
150MG | 30 Capsules | $195.81 | $6.53 |
Rifabutin Warnings
This safety information outlines important warnings and precautions for the use of rifabutin (Mycobutin). Please review these details carefully and consult your healthcare provider if you have any questions or concerns.
Tuberculosis Precaution: Rifabutin (Mycobutin) should not be used for the treatment of tuberculosis (TB). Utilizing it for TB prevention may lead to antibiotic resistance. If you have active TB, a combination of different anti-TB antibiotics is necessary. Your healthcare provider will assess you for TB before starting rifabutin and will monitor you regularly during the course of treatment to prevent a TB infection.
Drug Interactions: Rifabutin (Mycobutin) can interact with many medications, such as clarithromycin and protease inhibitors used in HIV treatment. Ensure that all your healthcare providers and pharmacists are informed of all the medications you are taking to avoid interactions and ensure appropriate dosing.
Allergic Reactions and Skin Issues: Serious allergic reactions, including anaphylaxis, can occur with rifabutin (Mycobutin). Seek immediate medical attention if you experience symptoms such as dizziness, rash, hives, facial or tongue swelling, difficulty breathing, or flu-like symptoms.
Eye Inflammation: Though rare, rifabutin (Mycobutin) can cause uveitis, an inflammation in the eye, especially if taken with medications like clarithromycin, azithromycin, or fluconazole. Notify your provider if you experience eye redness, pain, blurred vision, or sensitivity to light.
Infectious Diarrhea Risk: Antibiotics, including rifabutin (Mycobutin), can increase the risk of a serious gut infection leading to severe diarrhea, which may occur even after treatment completion. Contact your provider if you develop severe diarrhea with watery stools.
Blood Cell Monitoring: Rifabutin (Mycobutin) may lead to low counts of white blood cells and platelets. Regular blood tests will be conducted by your provider to monitor these levels during treatment.
Contraindications: Do not use rifabutin (Mycobutin) if you have an allergy to rifamycins. Consult your healthcare provider if this applies to you.
Rifabutin Side Effects
Common side effects:
- Change in urine color
- Low blood cell count
- Rash
- Higher liver enzymes
- Nausea
Less common but important to monitor:
- Stomach pain
- Fever
- Headache
- Low appetite
- Diarrhea
- Upset stomach
- Excessive gas
- Vomiting
- Muscle pain
- Change in taste
Serious side effects:
- Severe skin or allergic reactions (fever, body aches, rash, swelling of lips or tongue, trouble breathing, blistering or peeling skin)
- Infectious diarrhea (fever, fatigue, stomach pain, watery diarrhea, frequent loose stools)
Rifabutin Interactions
Rifabutin is an antibiotic commonly used to prevent and treat infections caused by certain bacteria, including Mycobacterium avium complex (MAC) in individuals with weakened immune systems. It's important to be aware that rifabutin can interact with various medications, potentially altering their effectiveness or increasing the risk of side effects.
One notable interaction occurs with certain antiretroviral drugs used to treat HIV. Rifabutin can affect the levels of these medications in the blood, which may require adjustments to their dosages to maintain their effectiveness and minimize side effects.
Additionally, rifabutin may interact with oral contraceptives, potentially reducing their effectiveness. Individuals using hormonal birth control methods should discuss alternative or additional contraceptive measures with their healthcare provider while taking rifabutin.
Other medications that may interact with rifabutin include antifungal agents, certain antibiotics, and drugs metabolized by the liver's cytochrome P450 enzyme system. These interactions can lead to either increased or decreased levels of the medications involved, affecting their efficacy and safety.
To ensure safe and effective treatment, it's crucial to inform your healthcare provider about all medications, supplements, and herbal products you are currently using before starting rifabutin. Your provider can assess potential interactions and make necessary adjustments to your treatment plan.
What is rifabutin used to treat?
Rifabutin is primarily used to treat and prevent Mycobacterium avium complex (MAC) infections, particularly in individuals with HIV. It is also used as part of combination therapy for tuberculosis in certain cases.
Is rifabutin a TB drug?
Yes, rifabutin is a medication used in the treatment of tuberculosis (TB). It is often used as part of a combination therapy for TB, especially in patients who are also receiving medications for HIV, due to its lower potential for drug interactions compared to rifampin.
Is rifabutin the same as rifampin?
Rifabutin and rifampin are not the same, though they are both antibiotics belonging to the rifamycin class. They are used to treat different types of bacterial infections and have different pharmacokinetic properties and side effect profiles. It is important to use them as prescribed by a healthcare professional for their specific indications.
What is the major adverse effect of rifabutin?
The major adverse effect of rifabutin is uveitis, which is an inflammation of the uvea in the eye. It can also cause other side effects such as neutropenia, rash, and gastrointestinal disturbances. Regular monitoring is recommended for patients on rifabutin therapy.
Can you substitute rifabutin for rifampin?
Rifabutin can sometimes be used as a substitute for rifampin, particularly in patients who are on medications that interact with rifampin or in those who experience adverse effects from rifampin. However, the decision to substitute should be made by a healthcare provider, as it depends on the specific clinical situation and the condition being treated. It is important to consult with a healthcare professional before making any changes to medication regimens.