Pyrazinamide Coupons & Discount Card – Guaranteed Prices from $42.60
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500MG, Pyrazinamide (30 Tablets)
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CVS
$42.60
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$46.01
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$77.87
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$82.01
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$83.94
COUPON PRICEPyrazinamide savings card
Show this card to your pharmacistCVS
$42.60
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Pyrazinamide dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 500MG | 30 Tablets | $43.59 | $1.45 |
Pyrazinamide Warnings
This medication comes with important safety considerations that you should be aware of. Below are key warnings and contraindications to guide safe use. Please discuss any concerns with your healthcare provider.
Liver Injury: Pyrazinamide may cause liver damage, especially in individuals with pre-existing liver conditions or those who consume alcohol frequently. A liver function test is necessary before starting the medication. Be vigilant for symptoms such as fever, loss of appetite, nausea, vomiting, dark urine, or a yellowing of the eyes or skin, as these may indicate liver issues. Contact your healthcare provider immediately if any of these symptoms occur.
Gout: The medication can elevate uric acid levels, potentially triggering gout flares. If you have a history of gout, inform your healthcare provider and provide details of your last flare-up. Your uric acid levels will be monitored before starting treatment. Report any joint pain or swelling during the course of therapy.
Diabetes Considerations: Although the relationship between diabetes and tuberculosis (TB) is not fully understood, diabetes might influence TB treatment efficacy. Disclose any diabetic condition to your healthcare provider to develop an appropriate management plan for both diabetes and TB.
Contraindications
Avoid using this medication if you have the following conditions, as it may result in significant health risks:
- Severe liver problems
- Frequent gout flares
Consult your healthcare provider if you fall into any of these categories or have questions regarding the use of this medication.
Pyrazinamide Side Effects
Common side effects:
- nausea
- vomiting
- loss of appetite
- muscle and joint aches
Less common but important to monitor:
- persistent nausea or vomiting
- severe stomach pain
- unusual tiredness
- yellowing of the skin or eyes
- dark urine
- changes in urine output
- painful or swollen joints
- gout-like symptoms
- sudden joint pain
Serious side effects:
- severe allergic reaction
- persistent fever
- swelling of lymph nodes
- rash
- itching
- swelling of the face, tongue, or throat
- severe dizziness
- difficulty breathing
Pyrazinamide Interactions
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Cyclosporine
- Ethionamide
- Rifampin
- Zidovudine
What are the main side effects of pyrazinamide?
The main side effects of pyrazinamide include liver toxicity, which can lead to elevated liver enzymes or hepatitis, and hyperuricemia, which may cause gout or joint pain. Other possible side effects are nausea, vomiting, loss of appetite, and rash. It is important for patients to be monitored regularly for liver function and uric acid levels while taking this medication.
What class of drug is pyrazinamide?
Pyrazinamide is classified as an antimycobacterial drug. It is primarily used in the treatment of tuberculosis.
Does pyrazinamide affect urine?
Yes, pyrazinamide can affect urine. It may cause the urine to appear darker than usual. Additionally, it can increase uric acid levels in the blood, which might lead to gout or kidney stones, potentially affecting urine output or causing discomfort during urination. It is important for individuals taking pyrazinamide to stay well-hydrated and report any unusual changes in urine to their healthcare provider.
What are the Class 1 TB drugs?
Class 1 TB drugs, also known as first-line antitubercular drugs, include isoniazid, rifampicin, ethambutol, and pyrazinamide. These medications are typically used in combination to treat active tuberculosis due to their effectiveness and lower toxicity compared to second-line drugs.
What is the most common side effect of pyrazinamide?
The most common side effect of pyrazinamide is joint pain, often referred to as arthralgia.